Protein Alignment CAH2 and CA7

DIOPT Version :10

• Sequence 1: NP_648555.1
• Gene: CAH2 / 39390
• FlyBaseID: FBgn0027843
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_005173.1
• Gene: CA7 / 766
• HGNCID: 1381
• Length: 264
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 103/271 - (38%)
• Similarity: 143/271 - (52%)
• Gaps: 27/271 - (9%)

  Fly    28 FGYEGRHGPEHWSEDYARCSGKHQSPINIDQVSAVEKKFPKLEFFNFKV-VPDNLQMTNNGHTVL 91
            :||....||.||.:.|....|..||||||....||..  |.|:...... ...:|.:|||||:|.
Human     7 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYS--PSLQPLELSYEACMSLSITNNGHSVQ 69

  Fly    92 VKMSYNEDEIPSVRGGPLAEKTPLGYQFEQFHFHWGENDTIGSEDLINNRAYPAELHVVLRNL-E 155
            |..: :.|:...|.||||  :.|  |:.:|||||||:...:|||..::.:::|:|||:|..|. :
Human    70 VDFN-DSDDRTVVTGGPL--EGP--YRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKK 129

  Fly   156 YPDFASALDKDHGIAVMAFFFQVGDKSTGGYEGFTNLLSQIDRKGKSVNMT--NP---LPLGEYI 215
            |..|..|.....|:||:..|.:.||:.. .....|:.|..:..||.....:  ||   ||...:
Human   130 YSTFGEAASAPDGLAVVGVFLETGDEHP-SMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRH- 192

  Fly   216 SKSVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFR--LLTANDD---HLKNNFRPIQ 275
                  |::|.|||||||.||.||||....||.|:|:|:..||  |.|:.||   |:.|||||.|
Human   193 ------YWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQ 251

  Fly   276 PLNDRTLYKNY 286
            ||..|.:..::
Human   252 PLKGRVVKASF 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	34..286	CDD:459707	101/263 (38%)
CA7	NP_005173.1	alpha_CA_VII	27..262	CDD:239402	96/249 (39%)