Protein Alignment CAH2 and ca12

DIOPT Version :10

• Sequence 1: NP_648555.1
• Gene: CAH2 / 39390
• FlyBaseID: FBgn0027843
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_001016431.1
• Gene: ca12 / 549185
• XenbaseID: XB-GENE-1015246
• Length: 335
• Species: Xenopus tropicalis
• Alignment Length: 326
• Identity: 91/326 - (27%)
• Similarity: 151/326 - (46%)
• Gaps: 39/326 - (11%)

  Fly    11 IVIAPILICASLVLAQDFGYEGRHGPEHWSEDYARCSGKHQSPINIDQ-VSAVEKKFPKLEFFNF 74
            :|:..:..|.:......:.|.|..|.:.|.::|..|.|.:||||:|.| :...:.....::...:
 Frog     6 LVLLALPSCQAASEGHGWAYIGTKGEKSWPKNYEFCGGVYQSPIDIHQDILQYDSSLQPVKLNGY 70

  Fly    75 KVVP-DNLQMTNNGHTVLVKMSYNEDEIPSVRGGPLAEKTPLGYQFEQFHFHWGENDT-IGSEDL 137
            .|.| ::..::||||||.:.:      :|:::    .:..|..|...|.|.|||:..| .|||..
 Frog    71 NVSPAESFTLSNNGHTVQMSL------VPTMQ----IKIAPFHYTASQLHLHWGQRGTQKGSEHC 125

  Fly   138 INNRAYPAELHVVLRNLE-YPDFASALDKDHGIAVMAFFFQVGDKSTGGYEGFTNLLSQIDRKGK 201
            |..:.:..|:|:|..|.: |.|..:|:.:..|:||:....:||..:. .:|...:.|..|..|.:
 Frog   126 IEGKRFAGEVHLVNYNSDKYSDITTAMKESDGLAVLGILLEVGPFNP-TFEKIISQLHSIGYKDQ 189

  Fly   202 SVNMTNPLPLGEYISKSVESYFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFRLLTANDD- 265
            ||.:.. ..:.|.:.|.::.|:.|.||||||||...|.|..|..|:.|:|:||........:.|
 Frog   190 SVQIAG-FNVQELLPKRLDEYYRYEGSLTTPPCYPSVLWTVFRNPVTISEEQLITLETALYSTDR 253

  Fly   266 ----HLKNNFRPIQPLNDRTLYKNYIEIPIHNMGSIPLVDAENAAGKWRAQAAAVLLPLVVLAAL 326
                .:.||:|.:||..||                  ||......|.....|.|.||.::|:.|:
 Frog   254 NESVQMTNNYRQLQPHGDR------------------LVSVSFREGVVLTIALACLLGVLVIIAV 300

  Fly   327 S 327
            :
 Frog   301 T 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	34..286	CDD:459707	78/260 (30%)
ca12	NP_001016431.1	alpha_CA_XII_XIV	30..278	CDD:239400	80/277 (29%)