Protein Alignment CAH2 and Ca4

DIOPT Version :10

• Sequence 1: NP_648555.1
• Gene: CAH2 / 39390
• FlyBaseID: FBgn0027843
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_062047.1
• Gene: Ca4 / 29242
• RGDID: 2242
• Length: 309
• Species: Rattus norvegicus
• Alignment Length: 280
• Identity: 95/280 - (33%)
• Similarity: 136/280 - (48%)
• Gaps: 39/280 - (13%)

  Fly    35 GPEHWSEDYARCSGKHQSPINIDQVSAVEKKFPKLEFFNFKVVPD---NLQMTNNGHTVLVKMSY 96
            |||.|:.|   |....||||||  |::..|..|.|..|.| |..|   ..::.||.|:  |:||.
  Rat    37 GPEQWTGD---CKKNQQSPINI--VTSKTKLNPSLTPFTF-VGYDQKKKWEVKNNQHS--VEMSL 93

  Fly    97 NEDEIPSVRGGPLAEKTPLGYQFEQFHFHWGENDTIGSEDLINNRAYPAELHVVLRNLEYPDFAS 161
            .||..  :.||.|    |..|:..|.|.||.|....|||..|:.:.:..|:|||.:.:...|...
  Rat    94 GEDIY--IFGGDL----PTQYKAIQLHLHWSEESNKGSEHSIDGKHFAMEMHVVHKKMTTGDKVQ 152

  Fly   162 ALDKDHGIAVMAFFFQVGDKSTGGYEGFTNLLSQIDR--KGKSVN---MTNPLPLGEYISKSVES 221
            ..|....|||:||..:||::...|::.....||::.:  ...:|:   :.:.||    ..|.:.:
  Rat   153 DSDSKDKIAVLAFMVEVGNEVNEGFQPLVEALSRLSKPFTNSTVSESCLQDMLP----EKKKLSA 213

  Fly   222 YFSYTGSLTTPPCSEEVTWIDFTTPIDITEKQLNAFRLLTANDD----HLKNNFRPIQPLNDRTL 282
            ||.|.||||||.|.|.|.|..|..||.|.:.|...|......|.    ::|:|.||:|||.:|.:
  Rat   214 YFRYQGSLTTPGCDETVIWTVFEEPIKIHKDQFLEFSKKLYYDQEQKLNMKDNVRPLQPLGNRQV 278

  Fly   283 YKNYIEIPIHNMG---SIPL 299
            :::      |..|   |:||
  Rat   279 FRS------HASGRLLSLPL 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAH2	NP_648555.1	Carb_anhydrase	34..286	CDD:459707	90/262 (34%)
Ca4	NP_062047.1	alpha_CA_IV_XV_like	47..280	CDD:239391	84/247 (34%)