Protein Alignment eIF3l and eif-3.L

DIOPT Version :10

• Sequence 1: NP_648553.1
• Gene: eIF3l / 39386
• FlyBaseID: FBgn0036258
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001335534.1
• Gene: eif-3.L / 24104220
• WormBaseID: WBGene00015920
• Length: 538
• Species: Caenorhabditis elegans
• Alignment Length: 513
• Identity: 206/513 - (40%)
• Similarity: 323/513 - (62%)
• Gaps: 18/513 - (3%)

  Fly    38 MPDNVKYFLINFCQAIKEGNLYDIQNMYENTFPQISDHHFDKTAWPEEQEVAAIV-DNDKVFLIL 101
            :|:.|..:|:.|.:.:.|.|:.:|..:|:..||.:::..|....||:|..|..|: ..:|:|:||
 Worm    30 VPNEVADYLVYFSRMVDEQNVPEILTLYDQAFPDLTERFFRDRMWPDENVVERIIGPGNKLFIIL 94

  Fly   102 YKELYYRHIHARIPGGPKLEQRINSFFNYCDFFNLIISAQNPVMLELPDIWLWELVDEFVYQFQN 166
            |||||||.::||...||.|..|..||.||.:.|:.::|:::|:.|.||::|||:::||||||||.
 Worm    95 YKELYYRQLYARNTRGPLLVHRYESFMNYQELFSELLSSKDPIPLSLPNVWLWDIIDEFVYQFQA 159

  Fly   167 FAQYRARLTEKSQDEIQQLCVN---HSNEWSILCILNVLHSLVDISNIKKQLEAI---SQGVDPQ 225
            |..|:|...:::.||::.| :|   :.|.|:|..:||:|:||:..|.|.:||:|:   .:..:|.
 Worm   160 FCLYKANPGKRNADEVEDL-INIEENQNAWNIYPVLNILYSLLSKSQIVEQLKALKSFQEKRNPD 223

  Fly   226 TVAGDFGKLSFYKMLGYFSLVGLLRVHSLLGDYYQAIKVLEPIEIHKKSAYSHIPACQISTSYYV 290
            :||.:||:...|..||||:|:||||.|.|||||:||:|.::.::|..|..|:.:|.|.::..|:|
 Worm   224 SVADEFGQSDLYFKLGYFALIGLLRTHVLLGDYHQALKTVQYVDIDPKGIYNTVPTCLVTLHYFV 288

  Fly   291 GFAYMMMRRYADAIRTFSDILLYIQRTK----QLYSTRSYQNDQINKQAEQMYHLLAICLVLHPQ 351
            ||:::|||.|.:|.:.|.:.||||||||    |..|.:::|.|.|.|..:|::|||||||.:.||
 Worm   289 GFSHLMMRNYGEATKMFVNCLLYIQRTKSVQNQQPSKKNFQYDVIGKTWDQLFHLLAICLAIQPQ 353

  Fly   352 CIDESIQQVLREKNYHDAMFKMQCGDLEVFKSFFVFACPRFVSPCPPAVDAPMDDYVKDPMEHQL 416
            .|||||...|.|: ..:.|..|..|:::.|::.|...||:|:||.....:..  :..|:|:..|.
 Worm   354 RIDESIASQLSER-CGERMMHMANGNIDEFRNAFATGCPKFLSPTTVVYEGV--NQSKEPLLRQT 415

  Fly   417 QVFMDEVRQQKDLPTTRSYLKLYTTLPLTKLASFIDPNASEDDVSKLLIRLLCFKHKMRNLVWSK 481
            |.|::.:..|..||..|.|||||||||..|||||:|  ..::.....:.:||.:|..:..|....
 Worm   416 QSFLEGIESQMALPVLRGYLKLYTTLPTKKLASFMD--VDDEHYDSFIGKLLTYKMIVNELGKEA 478

  Fly   482 GPSGLEGTFKSGSELDFYIDDDMIHIADTKVSHRYGDFFVRKILKFNDLNRKLKNINI 539
            |||..:.. :..:::|||:|.|||:||||||:...|:.|:|.|.|..::...||.::|
 Worm   479 GPSSADDD-EPQTDIDFYVDRDMINIADTKVARHVGEHFIRHIQKLQEVQDVLKRLDI 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3l	NP_648553.1	Paf67	122..527	CDD:463028	170/414 (41%)
eif-3.L	NP_001335534.1	Paf67	115..523	CDD:463028	170/414 (41%)