Protein Alignment eIF3l and eIF3l

DIOPT Version :10

• Sequence 1: NP_648553.1
• Gene: eIF3l / 39386
• FlyBaseID: FBgn0036258
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: XP_316190.3
• Gene: eIF3l / 1276800
• VectorBaseID: AGAMI1_008690
• Length: 539
• Species: Anopheles gambiae
• Alignment Length: 542
• Identity: 393/542 - (72%)
• Similarity: 459/542 - (84%)
• Gaps: 10/542 - (1%)

  Fly     1 MYGGDEYATNSDYYDDYAH-TGDPQLDMEYERNYYAARMPDNVKYFLINFCQAIKEGNLYDIQNM 64
            ||..:|.....  ||:|.: .|.|: |..|:|.|:.  |.::||.||:.||..||:|.:|:|||:
Mosquito     1 MYSNEEPWEGG--YDEYGYEMGMPE-DGMYDRGYFP--MHEDVKKFLMYFCTVIKDGVVYEIQNL 60

  Fly    65 YENTFPQISDHHFDKTAWPEEQEVAAIVDNDKVFLILYKELYYRHIHARIPGGPKLEQRINSFFN 129
            ||||||::|:.||:|.|||.|:|||.:||||.:||||||||||||:||||.|||.||||:|||:|
Mosquito    61 YENTFPKLSEQHFEKKAWPSEEEVAHLVDNDNLFLILYKELYYRHLHARIQGGPSLEQRLNSFYN 125

  Fly   130 YCDFFNLIISAQNPVMLELPDIWLWELVDEFVYQFQNFAQYRARLTEKSQDEIQQLCVNHSNEWS 194
            ||:|||.|:.::.||.|||||||||||:||||||||||||||||||:|:.:|:..|..|:|..|:
Mosquito   126 YCNFFNYILPSKEPVQLELPDIWLWELIDEFVYQFQNFAQYRARLTDKTDEEMDMLLNNNSKVWN 190

  Fly   195 ILCILNVLHSLVDISNIKKQLEAISQGVDPQTVAGDFGKLSFYKMLGYFSLVGLLRVHSLLGDYY 259
            ||||||||||||.:|.||.||||.:.|.||:.|||:||:.||||||||||||||||||||||||:
Mosquito   191 ILCILNVLHSLVSMSKIKDQLEAAAAGKDPEAVAGEFGRHSFYKMLGYFSLVGLLRVHSLLGDYH 255

  Fly   260 QAIKVLEPIEIHKKSAYSHIPACQISTSYYVGFAYMMMRRYADAIRTFSDILLYIQRTKQLYSTR 324
            |||||||||||||||.|||||:|||||||||||||||||||:|||||||.|||||||||||||.|
Mosquito   256 QAIKVLEPIEIHKKSQYSHIPSCQISTSYYVGFAYMMMRRYSDAIRTFSSILLYIQRTKQLYSAR 320

  Fly   325 SYQNDQINKQAEQMYHLLAICLVLHPQCIDESIQQVLREKNYHDAMFKMQCGDLEVFKSFFVFAC 389
            ||||||||||.:||||||||||||||||||||||||||||||||.|:|||||||:||::||||||
Mosquito   321 SYQNDQINKQTDQMYHLLAICLVLHPQCIDESIQQVLREKNYHDNMYKMQCGDLDVFRNFFVFAC 385

  Fly   390 PRFVSPCPPAVDAPMDDYVKDPMEHQLQVFMDEVRQQKDLPTTRSYLKLYTTLPLTKLASFID-- 452
            |:||||.||..|||::|||||.:|||:.||||||:||::|||.|||||||||||:.|||||:|
Mosquito   386 PKFVSPVPPPPDAPIEDYVKDALEHQINVFMDEVKQQQELPTIRSYLKLYTTLPIMKLASFMDRK 450

  Fly   453 --PNASEDDVSKLLIRLLCFKHKMRNLVWSKGPSGLEGTFKSGSELDFYIDDDMIHIADTKVSHR 515
              ....|..:..||.|||||||||:|:||:||.|||||.|:||||||||||.|||||||||||||
Mosquito   451 PQDEVDEQKLENLLTRLLCFKHKMKNVVWTKGSSGLEGKFQSGSELDFYIDKDMIHIADTKVSHR 515

  Fly   516 YGDFFVRKILKFNDLNRKLKNI 537
            |||||:||::||.||||:|..|
Mosquito   516 YGDFFIRKVMKFEDLNRRLHAI 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3l	NP_648553.1	Paf67	122..527	CDD:463028	317/408 (78%)
eIF3l	XP_316190.3	Paf67	118..527	CDD:463028	320/412 (78%)