Protein Alignment: CycA and CCNA1

• Sequence 1: NP_524030.2
• Gene: CycA
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_003905.1
• Gene: CCNA1
• HGNCID: 1577
• Length: 465
• Species: Homo sapiens
• Alignment Length: 409
• Identity: 156/410 (38%)
• Similarity: 230/410 (56%)
• Gaps: 71/410 (17%)

  Fly    53 NGNNNVPRPAGKVQVFRDVRNLNVDENVEYGAKKSNVVPVVEQFKTFSVYEDNNDTQVAPSGKSL 117
            :|:.|...||||    :.:.:..|.|..:.|               |.:|.|..:..
Human   108 SGSENAFPPAGK----KALPDCGVQEPPKQG---------------FDIYMDELEQG-------- 145

  Fly   118 ASLVDKENHDVKFGAGQKELVDYDLDSTPMSVTDVQ--------SPMSVDRSILGVIQSSDI-SV 173
                |:::..|:.|...:::  |::|:..:. :|:.        |||.||.|:|.  ||.|| |:
Human   146 ----DRDSCSVREGMAFEDV--YEVDTGTLK-SDLHFLLDFNTVSPMLVDSSLLS--QSEDISSL 201

  Fly   174 GTETGVSPTGRVKELPPRNDRQRFLEVVQYQMDILEYFRESEKKHRPKPLYMRRQKDISHNMRSI 238
            ||:.                    :.|.:|..:|.:|.||:|.:||||..||::|.||:..||:|
Human   202 GTDV--------------------INVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTI 246

  Fly   239 LIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPPEVGEF 303
            |:||||||.|||||..|||||:|.:||||||.|:|:|.||||||||||.:|:||||||||||.||
Human   247 LVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEF 311

  Fly   304 VFLTDDSYTKAQVLRMEQVILKILSFDLCTPTAYVFINTYAVLCDMPEKLKYMTLYISELSLMEG 368
            |::|||:|||.|:|:||.::||:|:|||..||...|:..|.....:..:.:.:..|::||||:|.
Human   312 VYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEA 376

  Fly   369 ETYLQYLPSLMSSASVALARHILGMEMWTPRLEEITTYKLEDLKTVVLHLCHTHKTAKEL---NT 430
            :.:|:|||||:::|:..||.:.:....|...|...|.|.|.:   :|..|...||...::   ..
Human   377 DPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSE---IVPCLSELHKAYLDIPHRPQ 438

  Fly   431 QAMREKYNRDTYKKVAMME 449
            ||:||||....|..|::||
Human   439 QAIREKYKASKYLCVSLME 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	Cyclin_N	206..332	CDD:278560	84/126 (67%)
		Cyclin_C	334..450	CDD:281044	38/120 (32%)
CCNA1	NP_003905.1	Cyclin_N2	71..>145	CDD:293109	12/56 (21%)
		Cyclin_N	214..340	CDD:278560	84/126 (67%)
		Cyclin_C	342..459	CDD:281044	38/120 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG5024
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3202
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D520533at33208
OrthoFinder	1	1.000				FOG0000124
OrthoInspector	1	1.000				T608785
orthoMCL	1	0.900				OOG5_126649
Panther	1	1.100			O	PTHR10177
Phylome	1	0.910		0.800	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
User_Submission	0	0.000	Not matched by this tool.
	10	9.830