Protein Alignment CycA and ccna2

DIOPT Version :10

• Sequence 1: NP_524030.2
• Gene: CycA / 39340
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Sequence 2: NP_694481.1
• Gene: ccna2 / 192295
• ZFINID: ZDB-GENE-020418-1
• Length: 428
• Species: Danio rerio
• Alignment Length: 479
• Identity: 171/479 - (35%)
• Similarity: 251/479 - (52%)
• Gaps: 95/479 - (19%)

  Fly     6 IH-QDMSNKENPGIKIPAGVKNTKQPLAVIGGKAEKNALAPRANFAVLNGNNNVPRPAGKVQVFR 69
            :| .|:.|:||              .|:.:.|.|.||.:..|.|   :|.|   |:.|....|..
Zfish     8 VHDSDIHNQEN--------------MLSRLRGAAAKNRVENREN---VNPN---PKAANNRTVLG 52

  Fly    70 DVRN---------------------LNVDENV-EYGAKKSNVVPVVEQFKTFSVYEDNND---TQ 109
            ::.|                     ...:||. .:|.:.||..|.     .|.::.|..|   ::
Zfish    53 ELENSQRRQLGLRGAKQGSGPQIIACKPEENARSFGERPSNRQPA-----AFQIHVDEPDGACSK 112

  Fly   110 VAPSGKSLASLVDKENHDVKFGAGQKELVDYDLDSTPM----SVTDVQSPM-SVDRSILGVIQS- 168
            .||..:|                        .:|.:|:    :||.::.|: ::|..:.....|
Zfish   113 KAPLQRS------------------------TMDCSPLTLNPTVTRLRQPLATIDLPLEASFDSP 153

  Fly   169 SDISVGTETGVSPTGRVKELPPRNDRQRFLEVVQYQMDILEYFRESEKKHRPKPLYMRRQKDISH 233
            .|:|| .:....||             ...||..|..:|..:.||.|.|.:||..|||:|.||::
Zfish   154 MDMSV-IDCEERPT-------------NVNEVSDYAAEIHTHLREMEVKSKPKAGYMRKQPDITN 204

  Fly   234 NMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQMAVVRSKLQLVGTAAMYIAAKYEEIYPP 298
            :||:||:||||||.|||||..|||||:|.|:|||||.|:|:|.||||||||||.:|:|:||||||
Zfish   205 SMRAILVDWLVEVGEEYKLQNETLYLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPP 269

  Fly   299 EVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLCTPTAYVFINTYAVLCDMPEKLKYMTLYISEL 363
            ||.|||::|||:|||.||||||.::|.:|||||..||...|:..|.:...:..|::.:::::.||
Zfish   270 EVAEFVYITDDTYTKKQVLRMEHLVLTVLSFDLAAPTINQFLTQYFLHQPVSSKVESLSMFLGEL 334

  Fly   364 SLMEGETYLQYLPSLMSSASVALARHILGMEMWTPRLEEITTYKLEDLKTVVLHLCHTHKTAKEL 428
            ||::.:.:|:||||.|::|:..||.|.|....|:..|.::|.|.||||...|..|..|:..|.:.
Zfish   335 SLIDCDPFLKYLPSQMAAAAFILANHTLASGSWSKSLVDLTGYSLEDLLPCVQDLHQTYLAASQH 399

  Fly   429 NTQAMREKYNRDTYKKVAMMESVE 452
            ..||:||||....|.:|:::|..|
Zfish   400 AQQAVREKYKGSKYHEVSLIEPPE 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycA	NP_524030.2	CYCLIN_CCNA_rpt1	202..329	CDD:410208	81/126 (64%)
		Cyclin_C	334..450	CDD:397230	40/115 (35%)
ccna2	NP_694481.1	Cyclin_N2	97..157	CDD:465146	14/88 (16%)
		CYCLIN_CCNA2_rpt1	171..301	CDD:410264	83/129 (64%)
		CYCLIN_CCNA2_rpt2	305..414	CDD:410267	38/108 (35%)