Protein Alignment Dnai2 and dync1i2b

DIOPT Version :10

• Sequence 1: NP_001261723.1
• Gene: Dnai2 / 39318
• FlyBaseID: FBgn0036195
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: XP_009300385.2
• Gene: dync1i2b / 561612
• ZFINID: ZDB-GENE-090121-1
• Length: 645
• Species: Danio rerio
• Alignment Length: 567
• Identity: 120/567 - (21%)
• Similarity: 216/567 - (38%)
• Gaps: 119/567 - (20%)

  Fly    13 GARVHFEDKDEVVFTENSNPELVKSYILKNPVDRVTQ--YAGQTSLSVANTERATYKSTGITHNE 75
            |.|....|.|......:|:.:|.:. .||..:.:|||  :..:..:|.:   :.|...|...|.|
Zfish   120 GPRTLHWDSDPSTLLLHSDSQLGRG-PLKLGMSKVTQVDFPPKEMVSYS---KETQTPTQTHHKE 180

  Fly    76 G-GWPKDINMHDPEQTVRYKRKIEKDENYITQVMNLTKPMEHYIHQNNAVNIYENYFENLDPAPL 139
            . ...:|:.:..|....:.::..:|:|:..:......:..:..:|....|..:::      .:.:
Zfish   181 DEEEEEDLAVMQPVMEPQEEKDSQKEEDEASPHELTEEEKQQILHSEEFVTFFDH------SSRI 239

  Fly   140 PEPCKSRTVNVYRDPN-------------PIKVPV----------KH-----LSWSPDGGIKMAV 176
            .|...|..|:|:.|.:             ..|:.:          ||     |.|||.....:..
Zfish   240 MERALSEQVDVFFDYSGRDLQDKEGESQAGAKLSLNRQFADERWSKHRVVTCLDWSPQYPELLVA 304

  Fly   177 SHCDMRFQGDKSNQKCNSYIWEVENPNEP----------FLTLEPKVPCVC------LEYNQKDP 225
            |:|        ||:         |.|:||          :....|:....|      ..:.|..|
Zfish   305 SYC--------SNE---------EAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSAAFAQFHP 352

  Fly   226 TSLVSGMYNGQVAAWDTRHGK------LPVMISEREVCHRDPVNSVLWNNSKSGTEFFSGGSDGQ 284
            ..:|.|.|:||:..||.|..|      .|:..|    .|..||..|....:::.....|..:||:
Zfish   353 NLVVGGTYSGQIVLWDNRSNKRTPVQRTPLSAS----AHTHPVYCVNVVGTQNAHNLISISTDGK 413

  Fly   285 VLWWDTRKLTEPLDRLLMDPVKSDDQDL----SRSYGISVLEYETTIPTRFMAGTEMGMLFSCNR 345
            :..|....|:.|.|.|          :|    |:|..::.:.:.......|:.|:|.|.:::..|
Zfish   414 MCSWSLDMLSTPQDSL----------ELVFKQSKSVAVTSMSFPLGDVNNFVVGSEDGSVYTACR 468

  Fly   346 KGKTPTEKIQIRMMC--HLGPVYAITRNPA-----FVKNFLTVG-DWCARIWSEDCRESSIIWT- 401
            .|    .|..|..|.  |.||:..:..:.|     |...|:|.. ||..::|.  .:.:..:::
Zfish   469 HG----SKAGISEMFEGHHGPITGLDCHTAAGPVDFSHLFVTSSFDWTVKLWG--TKNNKPLYSF 527

  Fly   402 KSSSSMLTDGAWSYTKVSQFFITRMDGV--LDTWDLLQQQNEPVLTVKVCDEP-LYCVRTNENGK 463
            :.:|..:.|..||.|..:.|  ..:|||  ||.|:|..:...|..:|.|...| |..||...:|:
Zfish   528 EDNSDYVYDVMWSPTHPALF--ACVDGVGHLDLWNLNNETEVPTASVTVEGNPALNRVRWAHSGR 590

  Fly   464 FVSCGSQLGATFLVEVSDNMVMSAKND-KPLLTAMFERENRREKILE 509
            .|:.|...|...:.:|.:.:.:..::: ...:..:.|....||.:.|
Zfish   591 EVAVGDSEGQLHIYDVGEQISVPRQDEWTRFVRTLTEINENREDVEE 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnai2	NP_001261723.1	WD40	212..469	CDD:475233	70/284 (25%)
		WD40 repeat	215..254	CDD:293791	14/50 (28%)
		WD40 repeat	262..304	CDD:293791	10/41 (24%)
		WD40 repeat	318..355	CDD:293791	7/36 (19%)
		WD40 repeat	365..401	CDD:293791	7/41 (17%)
		WD40 repeat	408..433	CDD:293791	10/26 (38%)
		WD40 repeat	162..208	CDD:293791	14/60 (23%)
dync1i2b	XP_009300385.2	None