Protein Alignment Dnai2 and Dync2i2

DIOPT Version :10

• Sequence 1: NP_001261723.1
• Gene: Dnai2 / 39318
• FlyBaseID: FBgn0036195
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001005542.2
• Gene: Dync2i2 / 296618
• RGDID: 1359465
• Length: 537
• Species: Rattus norvegicus
• Alignment Length: 518
• Identity: 106/518 - (20%)
• Similarity: 198/518 - (38%)
• Gaps: 105/518 - (20%)

  Fly    55 SLSVANTERATYKSTGITHNEGGWPKDINMHDPEQ-----------TVRYKRKIEKDENYITQVM 108
            |...|....|...:...||.:.    .:....||:           |:|....:.:.|..:.:.:
  Rat    64 SCQTAGIATAEASAQARTHADA----QVQTEAPEEPAAVAPVSQYDTLRLAAFLRRVEAMVVREL 124

  Fly   109 NLTKPMEHYIHQNNAVNIYE-NYFENLDPAPLPEPCKSRTVNV-----YRDPNPIKVPVKHLSWS 167
            |..       .|::|.:.|| |:.|           :.:||:.     |.......:.|..:||:
  Rat   125 NNN-------WQSHAFDGYEVNWTE-----------QQQTVSCLHTLGYPPAQGQGLHVTGISWN 171

  Fly   168 PDGGI-KMAVSHCDMRFQGDKSNQKCNSYI--WEVE----NPNEPFLTLEPKVPCVCLEYNQKDP 225
            ..|.: ..|....|   .||....|  ||:  |.::    ||::|.:.:|.....:||.::...|
  Rat   172 TTGSVLACAYGRLD---DGDWGTLK--SYVCTWNLDRQGLNPHQPSVVVEVPSAVMCLAFHPIQP 231

  Fly   226 TSLVSGMYNGQVAAWDTRHGKLPVM--ISEREVCHRDPVNSVLWNNSKSGTEFF---SGGSDGQV 285
            :.:..|:|:|:|..||....:.|::  ....:..|.|||..|||......:..|   |..:||:|
  Rat   232 SHIAGGLYSGEVLVWDMSRPEDPLLWRTGLTDDTHTDPVYQVLWLPEPRHSHRFQVLSAATDGRV 296

  Fly   286 LWW-----DTRKLTE---------PLDRLLMDPVKSDDQDLSRSYGISVLEYETTIPTRFMAGTE 336
            |.|     ...:|::         |....|..|.:.:.:     .|::.:.:.:...:.|:.|||
  Rat   297 LLWRGSGAGQLRLSKGFALAVQQLPRSTKLKKPPRGETE-----VGVTSVAFSSFDSSLFVLGTE 356

  Fly   337 MGMLFSCNRKG------KTPTE-----KIQIRMMCHLGPVYAITRNPAFVKNFLTVG-DWCARIW 389
            .|....|:...      :.|:.     .:|.....|.||||:::.:|.....||:.| |....::
  Rat   357 GGFPLKCSLAAEAAALTRMPSSVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTDGHVHLY 421

  Fly   390 SEDCRESSIIWTKSSSSMLTDGAWSYTKVSQFFITRMDGVLDTWDLLQQQNEPVLTVKVCDE--P 452
            |. .:...:...:.|...|....||..:...|.....:|.:..:||.:...:|.:::....:  |
  Rat   422 SM-LQAQPLTSLQLSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSP 485

  Fly   453 LYCVRTN-ENGKFVSCGSQLGATFLVEVSDNMVMSAKNDKPLLTAMFERENRREKILEAKSRE 514
            :||:..| :..:.::.|...|...:.::|              ||..|:..|..:.|:....|
  Rat   486 VYCLEFNSQQTQLLAAGDAKGVVKVWQLS--------------TAFTEQGPREAEDLDQLEAE 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnai2	NP_001261723.1	WD40	212..469	CDD:475233	61/290 (21%)
		WD40 repeat	215..254	CDD:293791	10/40 (25%)
		WD40 repeat	262..304	CDD:293791	14/58 (24%)
		WD40 repeat	318..355	CDD:293791	7/47 (15%)
		WD40 repeat	365..401	CDD:293791	8/36 (22%)
		WD40 repeat	408..433	CDD:293791	5/24 (21%)
		WD40 repeat	162..208	CDD:293791	14/52 (27%)
Dync2i2	NP_001005542.2	WD40	50..515	CDD:441893	100/497 (20%)
		WD40 repeat	165..211	CDD:293791	14/50 (28%)
		WD40 repeat	223..265	CDD:293791	10/41 (24%)
		WD40 repeat	271..309	CDD:293791	10/37 (27%)
		WD40 repeat	339..389	CDD:293791	8/49 (16%)
		WD40 repeat	396..433	CDD:293791	8/37 (22%)
		WD40 repeat	439..479	CDD:293791	8/39 (21%)
		WD40 repeat	486..511	CDD:293791	5/24 (21%)