Protein Alignment Dnai2 and dnai3

DIOPT Version :10

• Sequence 1: NP_001261723.1
• Gene: Dnai2 / 39318
• FlyBaseID: FBgn0036195
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001120428.1
• Gene: dnai3 / 100145513
• XenbaseID: XB-GENE-980327
• Length: 896
• Species: Xenopus tropicalis
• Alignment Length: 727
• Identity: 151/727 - (20%)
• Similarity: 260/727 - (35%)
• Gaps: 210/727 - (28%)

  Fly     1 MEYIFKKERRSFGARVHFEDKDEVVFTENSNPELVKSYILKNPVDRVTQYAGQTSLSVANTERAT 65
            ::::..:.:|.|||:|:|.|       .|::.       :|:.....|.|..: ..|:...||.|
 Frog   193 IKFMISRIQRKFGAKVNFGD-------HNASD-------VKDGYMECTSYQDK-RFSIKINERDT 242

  Fly    66 ------YKSTGITHNEGGWPKD-INMHDPEQTVRYKRKI---EKD-ENYITQVMNLTKPMEHYIH 119
                  :.....|..:.|:|:: ...:.|.:....:||.   .|| ::::..|   :..:|..:.
 Frog   243 GIQVVPFTQENSTQTKWGYPRNACTQYTPREFTEEERKACLSSKDFKDFVNSV---SLRLELALQ 304

  Fly   120 QNNAVNIY----------ENYFENLDPAPLPEPCKSRTVNVYRDPNPIKVPVKHLSWSPDGGIKM 174
            ||..:|.:          ||.|.....:.|.| .:|.|.:::.:...|    ..::|.|.....:
 Frog   305 QNEIMNAFLDDWKALSEEENTFGGKSDSHLKE-SQSFTDHLFSNAKTI----SGINWHPKIHGLV 364

  Fly   175 AVSHCDMRFQGDKSNQKCNSYI-------WEVENPNEPFLTLEPKVPCVCLEYNQKDPTSLVSGM 232
            |||..:.....|:.|......:       |...:|..|.|.||......|.::...||..:..|.
 Frog   365 AVSMTERLSFEDRVNISSKILLKPSLILFWSFTDPLHPQLMLECPDDIYCFQFCPSDPNIIAGGC 429

  Fly   233 YNGQVAAWDTRHGKLPVM------------------------------ISEREVCHRDPVNSVLW 267
            :||||..||....:..:|                              :|..|..|::.:..:.|
 Frog   430 FNGQVVLWDISKYQESLMAKAGVSKNTAPKTGLEPSVPKGPQLVRYCAVSSIEHGHKNVITDIHW 494

  Fly   268 --NN-----------SKSG--TEFFSGGSDGQVLWWDTRKLTEPLDRLLMDPVKSDDQDLSRSYG 317
              ||           :|||  .:..:...|..:::||.|.     .:.|....|.:.:|....:|
 Frog   495 LPNNFELSNAGNPYENKSGYCLQLVTCSPDCSIMFWDIRP-----QKTLTAAEKKNVEDKQMPHG 554

  Fly   318 I----------------------------------------------------------SVLEYE 324
            :                                                          .|:||:
 Frog   555 VPDTFKYIDLTWRPFIRAILPKSDMSGEYSPMKISLSEEHHHCRTLDKLQIQAKEDKTEGVVEYK 619

  Fly   325 T-------------TIPTRFMAGTEMGMLFSCNRK-------GKTPTEKIQIRMMCHLGPVYAIT 369
            :             .|.|::..|||.|.|...:.|       ||..:.|.....:.|.|.|..:.
 Frog   620 SLRAASAKNPKLLDDINTKYFVGTEDGELVYTDWKMEKDSDTGKLISSKPLQANILHDGAVNTVQ 684

  Fly   370 RNPAFVKNF-LTVGDWCARIWSEDCRESSIIWTKSSSSMLTDGAWSYTKVSQFFITRMDGVLDTW 433
            |:| |:|:| ||||.|...||.|......|..:..|...||...||.::...|||.:.||.:|.|
 Frog   685 RSP-FLKDFILTVGGWNFAIWREGVTSGPIFHSCCSQKRLTAAHWSLSRTGVFFIGKEDGNVDVW 748

  Fly   434 DLLQQQNEPVLTVKVCDEPLYCVR---TNENGKFVSCGSQLGATFLVEVSDNMVMSAKNDKPLLT 495
            |||::.:||..|..:...|:..:|   .:....|::.|...|...::|:..|:...:.|:...:.
 Frog   749 DLLEKTHEPSQTQNIAAAPITYIRPWIASSKQHFLAVGDDQGTLHILEIPWNLRHPSANENASVQ 813

  Fly   496 AMFERE-------NRREKILEAKSRESKLKVKANHGQDQGDTMMVNGKINMAPFEAACEQAASEY 553
            ..||||       |:||.:.....::.:||             .::.|...:|.....||
 Frog   814 HYFEREVKHVEYSNQREGLRATAKKQLELK-------------DLSAKTETSPPVKTKEQ----- 860

  Fly   554 FAAVEQERQRRL 565
             ..|||.::..|
 Frog   861 -TEVEQSKEYEL 871

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dnai2	NP_001261723.1	WD40	212..469	CDD:475233	80/383 (21%)
		WD40 repeat	215..254	CDD:293791	12/68 (18%)
		WD40 repeat	262..304	CDD:293791	11/56 (20%)
		WD40 repeat	318..355	CDD:293791	14/114 (12%)
		WD40 repeat	365..401	CDD:293791	15/36 (42%)
		WD40 repeat	408..433	CDD:293791	10/24 (42%)
		WD40 repeat	162..208	CDD:293791	10/52 (19%)
dnai3	NP_001120428.1	None