DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14135 and AgaP_AGAP005574

DIOPT Version :9

Sequence 1:	NP_001261721.1	Gene:	CG14135 / 39316	FlyBaseID:	FBgn0036193	Length:	259	Species:	Drosophila melanogaster
Sequence 2:	XP_556220.3	Gene:	AgaP_AGAP005574 / 3290002	VectorBaseID:	AGAP005574	Length:	580	Species:	Anopheles gambiae

Alignment Length:	285	Identity:	63/285 - (22%)
Similarity:	104/285 - (36%)	Gaps:	99/285 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 CAVKNCGNNNRIANRTKWRY-FHF--PKEKPNLQRWIDFCQR--DNINPTTACICNEHFAPNDFE 62
            |:...|.||....||..... ||.  |....|:::||:||||  |.:....:.:|:.||..:||:
Mosquito     6 CSASFCKNNRYNVNRRGLDITFHTFPPLNYHNVRQWIEFCQREEDWLPNKHSVLCSAHFRDDDFQ 70

  Fly    63 RNMQYELGFSRKNPTKLKPGSFPSVNGPQKLAKELRGSIKRGSKSVP---LAGSTKMSNIGF--- 121
            .|          |...:|.|         |..:.|:|.......|.|   |:...|:..:..
Mosquito    71 MN----------NCPIIKQG---------KRLRHLKGYAVPSVMSRPPITLSKRQKLDEVRIKLL 116

  Fly   122 ------DPHHAGTQSSEGHETIEIQLCGFNTDIEGFEEAEDDDCPSGPRLVEVEILDPLNPQSNA 180
                  |.|:.|   ||...|              :.||:.|         |....||||   ..
Mosquito   117 ANLYNKDEHNTG---SENDHT--------------YSEAKTD---------EPVQRDPLN---GC 152

  Fly   181 KDHVEIID------------SEGDSYVK-----HLELEICSLKREVFFLKDEY------QKIKAE 222
            |..:..:.            .|.||...     |..|| |::::::    ||.      |:.:::
Mosquito   153 KKSIYFLQRYPNVCAFCLRLMEDDSVFLPLGHFHDSLE-CTIEQKL----DEITGDPMDQEDRSD 212

  Fly   223 MRNLKDTIKRSEEELAEKQLQGVVK 247
            ::||      ..:::.|:.|:.::|
Mosquito   213 VQNL------LPDKVCEECLETLIK 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14135	NP_001261721.1	THAP	2..88	CDD:283206	26/89 (29%)
CG14135	NP_001261721.1	GrpE	198..>239	CDD:295646	8/46 (17%)
AgaP_AGAP005574	XP_556220.3	THAP	5..96	CDD:214951	29/108 (27%)
AgaP_AGAP005574	XP_556220.3	zf-AD	165..238	CDD:214871	15/78 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008566
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910