Protein Alignment TfIIEalpha and gtf-2E1

DIOPT Version :9

• Sequence 1: NP_524026.1
• Gene: TfIIEalpha / 39313
• FlyBaseID: FBgn0015828
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_503060.1
• Gene: gtf-2E1 / 178502
• WormBaseID: WBGene00013998
• Length: 433
• Species: Caenorhabditis elegans
• Alignment Length: 455
• Identity: 116/455 - (25%)
• Similarity: 220/455 - (48%)
• Gaps: 59/455 - (12%)

  Fly     3 STSTAAANAAPAKTEVRYVTEVPSSLKQLARLVVRGFYSLEDALIIDMLVRNPCMKEDDIGELLR 67
            |:..|.:.::.|.||.:.|.|:|.:|..:..:||:.|:|.|..:|:..::|..|::|:::...::
 Worm     2 SSGPATSGSSSAHTETQVVDEIPEALNTILLMVVKNFFSSEHFIIVYHIMRAQCIREENLKARIQ 66

  Fly    68 FEKKQLRARITTLRTDKFIQIRLKMETGPDGKAQKVNYYFINYKTFVNVVKYKLDLMRKRMETEE 132
            |::|.||..:.:|:.:|.::.|...:...:.:...:.:|:|||:..:|||:||:|.||:::|:.|
 Worm    67 FDQKMLRQLLASLKAEKLVKERTITQKNENNRTVSIIFYYINYRAVLNVVRYKIDHMRQKLESRE 131

  Fly   133 RDATSRASFKCSSCSKTFTDLEADQLFDMATLEFRCTFCGSSVEEDSAAMPKKDSRLMLAHFNEQ 197
            :..|:||.::|.:|..::..||.:::.|..:....|..|...|..|...:|.:.:|..:|.||||
 Worm   132 QMDTNRAHYRCGACQSSYDMLEINRILDAESGRLICWRCHGDVLADETVVPSRTTRTAVARFNEQ 196

  Fly   198 LQPLYDLLREVEGIKLAPEVLEP--------------EPVDIDTIRGLNKPNATRPDGMAWSGEA 248
            :.||:..:..:.||:|||.:|||              :...:|...|.......:..|:|.|.:.
 Worm   197 MTPLFSHICALNGIQLAPHLLEPDITKYLEDDKELQLQQQQMDFTSGGGGGGRIQLGGVAHSYQN 261

  Fly   249 TRNQGFAVEETRVDVTIGGDDTSDAVIERKSRPIWMTESTVITDTDAADGAADAVQTASGSGHRN 313
            ..:..:...:. |.|.:..|.....|.|.|..|.|:.::.:                  |.|..:
 Worm   262 IASINYQNGDA-VFVDLNADINKGPVEEAKIMPEWLKDNAI------------------GGGEAS 307

  Fly   314 RKENEDIMSVLLQHEKQPGQKEPHMKGMRVGSS-------NANSSDSSDDEKDIENSKIPDVDFD 371
            ..|:     ||.|.:.:  ::|...|..|.|.|       ..:|.:|:.:.| ||......:..:
 Worm   308 HNEH-----VLDQAKTE--EEETSTKQRRYGPSLDYLKEIECSSEESAPNVK-IEEPPAKQIKME 364

  Fly   372 -------NYINSDSAEEDDDVPTVLVAGRPHPLDQLDDNLIA-QMTPQEKENYIHVYQQHYSHIF 428
                   ..:::|.:||:|   .:.||||..||.|:...::. :|:..|||:|..|.|..::..|
 Worm   365 VDEEAIKMEVDNDESEEED---LIHVAGRALPLSQITPRMVENEMSELEKESYCSVVQDLFAMFF 426

  Fly   429  428
             Worm   427  426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIEalpha	NP_524026.1	HTH	30..137	CDD:304362	30/106 (28%)
		TFIIE	43..188	CDD:128804	39/144 (27%)
		TFIIE-A_C	357..429	CDD:288386	22/80 (28%)
gtf-2E1	NP_503060.1	TFIIE	41..188	CDD:128804	39/146 (27%)
		TFIIE-A_C	354..426	CDD:371578	19/74 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160161028
Domainoid	1	1.000	75	1.000	Domainoid score	I5892
eggNOG	1	0.900	-	-		E1_COG1675
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38062
Inparanoid	1	1.050	168	1.000	Inparanoid score	I2774
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52052
OrthoDB	1	1.010	-	-		D1343016at2759
OrthoFinder	1	1.000	-	-		FOG0003249
OrthoInspector	1	1.000	-	-		oto20157
orthoMCL	1	0.900	-	-		OOG6_104238
Panther	1	1.100	-	-	LDO	PTHR13097
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1464
SonicParanoid	1	1.000	-	-		X4875
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840