Protein Alignment CG32085 and CG12402

DIOPT Version :10

• Sequence 1: NP_729732.1
• Gene: CG32085 / 39311
• FlyBaseID: FBgn0052085
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001303481.1
• Gene: CG12402 / 41714
• FlyBaseID: FBgn0038202
• Length: 671
• Species: Drosophila melanogaster
• Alignment Length: 719
• Identity: 141/719 - (19%)
• Similarity: 238/719 - (33%)
• Gaps: 250/719 - (34%)

  Fly    76 GNSNSNSGSNSS-----------------------NSNTSSASATAATSPASNANPPQTP----- 112
            |||...||..|.                       |.|...|.|.:..:|.:   ||.||
  Fly     2 GNSLITSGKPSQRREKRLFERLSCSYAQTPNRMELNLNPLLAIARSIAAPPT---PPPTPEKLDS 63

  Fly   113 DKPSRGSSPSPGGITMPG-----------------------------------GQSQVQNSTHHL 142
            ||...|||.:...: :|.                                   .:.:|..:.|:|
  Fly    64 DKDKEGSSKAAIEL-LPNEMWLEIMSYLSYNDLLQLRMVSWRCRDLVHRRRFMEKGKVIVTQHNL 127

  Fly   143 -----------------------LQQQQQQQQHMQLQQSQQQHLQLQ------------------ 166
                                   |:|.:|.:..::|...:.:|||::
  Fly   128 EAIHKHAKGGNCYLSFERIELRNLRQCRQLENFLRLVGHEVKHLQVRHAPVFRNLDGKLPNLKVL 192

  Fly   167 --ASTLINSNHHVMVGPAPPTGMPLGAPPTPTVKSIAKQMNITIPGGGVNPGSPTFSTMGMVAAQ 229
              |:|:...:.|            |.|.....:|..:..:.....|..::    ....|.|:
  Fly   193 TIATTMSMDDQH------------LAAMDDLDMKQFSHLVGFECDGVSLD----AVLKMRML--- 238

  Fly   230 KAAASAGGTPLQLRK---QLPNPHLHHPYGSMGINAASPLIMQHQLHPPPIHSIEQLMLDDRFLS 291
                      ||||:   ::...||...:.....||...::..|         .|.|:..:.|.|
  Fly   239 ----------LQLRRTENKVQLRHLQFEFRRNNENALLDVLQDH---------AETLVCVNLFFS 284

  Fly   292 RFFQYFSPYERRILAQVCIKWRDTLYRSPRYWSGLLPTLQCRELRQMPGCDRGK--------LYN 348
                             |....||     |.|        ||....|......|        |..
  Fly   285 -----------------CSPGIDT-----REW--------CRAFENMHNLRTLKLSGNCHLVLLE 319

  Fly   349 SLIR--------RGFHALGLVGASDEDALDVVHSFPLASKHVHSLS----LRCSSISDRGLETLL 401
            :::|        |.....|::..::|..|.|      |.|...:|.    :.|..::...::.|.
  Fly   320 AVLRAVPESAPIRQLDLTGMLSLTNELLLYV------AGKWQSTLKVLDLMFCVQLNANCIDALR 378

  Fly   402 DHLQSLFELELAGCNEVTEAGLWACLTPRI----VSLSLADCINIADEAVGAVAQLLPSLYEFSL 462
            .....|..|.:|.|.|:|..||...|...|    ..|.|.:.|.:.:.::..:.:.||:|...||
  Fly   379 QLSGRLEALTMAYCRELTGTGLLQGLAGDINYSLQELHLEETIFLDESSMCQLLERLPNLRRLSL 443

  Fly   463 ----QAYHVTDAALGYFSPKQSHSLSILRLQSCWELTNHGIVNI------VHSLPHLTVLSLSGC 517
                ||  |||..:......|:. |..|.::.|.::|:.|::..      :..|..|..|:|.||
  Fly   444 DNCRQA--VTDRTMATICQYQTR-LRNLNIEYCMKITDQGLMGYGDTPYPISRLRGLKELNLRGC 505

  Fly   518 SKLTDDGVELIAENLQKLRALDLSWCPRITDASLEYIACDLNQLEELTLDRCVHITDIGVGYIST 582
            ..:||..: ::...|.:||||.|.:|.|:|....|.:..:...||.|.:..|:.:.|      .|
  Fly   506 RNVTDSSL-MVGLKLPELRALSLGYCNRLTSEGFEALTQNCPSLEALCVSSCMAVDD------ET 563

  Fly   583 MLSLTALFLRWCSQVRDFGLQHLCSMRNLQVLSLAGCPLLTSSGLSSLIQLRH-LQELELTNCPG 646
            :|::.:                  :::.|:||:|:.|..||...:..::...| |.:|...:..|
  Fly   564 VLNIVS------------------NLKRLRVLNLSNCTKLTLQSIHHILAHGHNLVQLIACSIDG 610

  Fly   647 ASHE 650
            ..||
  Fly   611 MDHE 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	F-box_FBXL16	283..325	CDD:438899	8/41 (20%)
		leucine-rich repeat	382..406	CDD:275381	3/27 (11%)
		AMN1	383..600	CDD:187754	57/234 (24%)
		leucine-rich repeat	431..456	CDD:275381	5/28 (18%)
		leucine-rich repeat	457..482	CDD:275381	9/28 (32%)
		leucine-rich repeat	483..508	CDD:275381	6/30 (20%)
		leucine-rich repeat	509..534	CDD:275381	8/24 (33%)
		leucine-rich repeat	535..560	CDD:275381	9/24 (38%)
		leucine-rich repeat	561..585	CDD:275381	6/23 (26%)
		leucine-rich repeat	586..610	CDD:275381	0/23 (0%)
		leucine-rich repeat	636..661	CDD:275381	5/15 (33%)
CG12402	NP_001303481.1	F-box	75..117	CDD:425796	1/42 (2%)
		leucine-rich repeat	281..303	CDD:275381	10/51 (20%)
		PPP1R42	<297..482	CDD:455733	43/193 (22%)
		leucine-rich repeat	304..330	CDD:275381	3/25 (12%)
		leucine-rich repeat	331..357	CDD:275381	7/31 (23%)
		leucine-rich repeat	358..379	CDD:275381	3/20 (15%)
		leucine-rich repeat	384..409	CDD:275381	9/24 (38%)
		leucine-rich repeat	412..437	CDD:275381	4/24 (17%)
		AMN1	430..595	CDD:187754	48/192 (25%)
		leucine-rich repeat	438..464	CDD:275381	9/27 (33%)
		leucine-rich repeat	465..496	CDD:275381	6/30 (20%)
		leucine-rich repeat	497..521	CDD:275381	8/24 (33%)
		leucine-rich repeat	522..547	CDD:275381	9/24 (38%)
		leucine-rich repeat	548..573	CDD:275381	7/48 (15%)
		leucine-rich repeat	574..599	CDD:275381	7/24 (29%)