Protein Alignment CG32085 and Fbxl17

DIOPT Version :10

• Sequence 1: NP_729732.1
• Gene: CG32085 / 39311
• FlyBaseID: FBgn0052085
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_038939705.1
• Gene: Fbxl17 / 316663
• RGDID: 1309773
• Length: 739
• Species: Rattus norvegicus
• Alignment Length: 751
• Identity: 140/751 - (18%)
• Similarity: 236/751 - (31%)
• Gaps: 288/751 - (38%)

  Fly    47 SPAGATPTPAAPSGKTSVMERVTNALCGGGNSNSNSGSNSSNSNTSSASATAATSPAS-NANPPQ 110
            :||.|:|.||||..:.... |....||                  ....:..|.:||. ...||.
  Rat    37 TPAKASPQPAAPRSRDCFF-RGPCMLC------------------FIVHSPGAPAPAGLEEEPPL 82

  Fly   111 TPDKPSRGSSPSPGGITMPGGQSQVQNSTHHLLQQQQQQQQHMQLQQSQQQHLQLQASTLINSN- 174
            :|  |.|           .|..:.|  |:.||.::............:::..|...|:...:|:
  Rat    83 SP--PPR-----------DGAYATV--SSQHLARRYAALAAEDCAAAARRFLLSSAAAAAASSSP 132

  Fly   175 ----------------------HHVMVGP----APPTGMPL--GAP------PTPTVKSIAKQMN 205
                                  ....|||    .||..:.|  |:|      ||..::.:.|:..
  Rat   133 ASCCKELGLAAAAAWEQQGRSLFLAGVGPVRFLGPPAAVQLFRGSPAPPQAEPTTVLEMVCKRKG 197

  Fly   206 ITIP--------------------------GGGVN-----------------------PGSPTFS 221
            ..:|                          |||.:                       |.||...
  Rat   198 AGVPACTPCKQPRCGGGGCGGGGGGGGGPAGGGASPPRPPDAGCCQAPEQPPPPLCPAPASPASE 262

  Fly   222 TMGMVAAQKAAASAGGTPLQLRKQLP------------NP---HLHHPYGSMGINAASPLIMQHQ 271
            ...:.||...|..||||.....:|.|            ||   |...|.....||...|.|:
  Rat   263 CAPIEAAAGDAVRAGGTAPSSAQQQPESGDSDCQEPPENPCDCHREPPPEIPDINQLPPSIL--- 324

  Fly   272 LHPPPIHSIEQLMLDDRFLSRFFQYFSPYERRILAQVCIKWRDTLYRSPRYWSGLLPTLQCRELR 336
                 :.....|.||:|.||             .:.||..||| |....::|..|
  Rat   325 -----LKIFSNLSLDERCLS-------------ASLVCKYWRD-LCLDFQFWKQL---------- 360

  Fly   337 QMPGCDRGKLYNSLIRRGFHALGLVGASDEDALDVVHSFPLASKHVHSLSLRCSSISDRGLETLL 401
                                                           .||.| ..::|..||.:.
  Rat   361 -----------------------------------------------DLSSR-QQVTDELLEKIA 377

  Fly   402 DHLQSLFELELAGCNEVTEAGLWACL----TPRIVSLSLADCINIADEAVGAVAQLLPSLYEFSL 462
            ...|::.|:.::.|..::::|:  |:    .|.::..:...|..::|.::.|||...|     .|
  Rat   378 SRSQNIVEINISDCRSMSDSGV--CVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCP-----LL 435

  Fly   463 QAYHVTDAALGYFSPKQSHSLSILRLQSCWELTNHGIVNIVHSLPHLTVLSLSGCSKLTDDGVEL 527
            |..||.:..                     :||:.|:..:......|..:....|.|::|:|:.:
  Rat   436 QKVHVGNQD---------------------KLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMVV 479

  Fly   528 IAENLQKLRALDLSWCPRITDASLEYIACDLNQLEELTLDRCVHITDIGVGYISTMLSLTALFLR 592
            ||::..||:.:.:.....:||.|::..|.....|:.:....| .:|..||.:::.:.:|::|.||
  Rat   480 IAKSCLKLQRIYMQENKLVTDQSVKAFAEHCPDLQCVGFMGC-SVTSKGVIHLTKLRNLSSLDLR 543

  Fly   593 WCSQV------------RDFGLQHLC---------------SMRNLQVLSLAGCPLL------TS 624
            ..:::            ::....:||               ..::|:.|.|..|.:.      .|
  Rat   544 HITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQSLKELYLVSCKITDYGQRGNS 608

  Fly   625 SGLSSLIQLRHLQELELTNCPGASHELFDYLKEHLP 660
            ....:.:...|||     :||..   |.:.|.|.||
  Rat   609 GAAGTAVPSHHLQ-----HCPAG---LQEDLGESLP 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	F-box_FBXL16	283..325	CDD:438899	13/41 (32%)
		leucine-rich repeat	382..406	CDD:275381	6/23 (26%)
		AMN1	383..600	CDD:187754	47/232 (20%)
		leucine-rich repeat	431..456	CDD:275381	5/24 (21%)
		leucine-rich repeat	457..482	CDD:275381	4/24 (17%)
		leucine-rich repeat	483..508	CDD:275381	3/24 (13%)
		leucine-rich repeat	509..534	CDD:275381	7/24 (29%)
		leucine-rich repeat	535..560	CDD:275381	5/24 (21%)
		leucine-rich repeat	561..585	CDD:275381	5/23 (22%)
		leucine-rich repeat	586..610	CDD:275381	6/50 (12%)
		leucine-rich repeat	636..661	CDD:275381	9/25 (36%)
Fbxl17	XP_038939705.1	F-box_FBXO13	315..363	CDD:438864	18/126 (14%)
		leucine-rich repeat	357..382	CDD:275381	8/82 (10%)
		leucine-rich repeat	383..408	CDD:275381	4/26 (15%)
		AMN1	406..568	CDD:187754	36/188 (19%)
		leucine-rich repeat	409..434	CDD:275381	6/29 (21%)
		leucine-rich repeat	435..460	CDD:275381	7/45 (16%)
		leucine-rich repeat	461..486	CDD:275381	7/24 (29%)
		leucine-rich repeat	487..512	CDD:275381	5/24 (21%)
		leucine-rich repeat	513..536	CDD:275381	5/23 (22%)
		leucine-rich repeat	537..562	CDD:275381	4/24 (17%)
		leucine-rich repeat	563..588	CDD:275381	2/24 (8%)