Protein Alignment CG32085 and gadr-4

DIOPT Version :10

• Sequence 1: NP_729732.1
• Gene: CG32085 / 39311
• FlyBaseID: FBgn0052085
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001317764.1
• Gene: gadr-4 / 173745
• WormBaseID: WBGene00021053
• Length: 797
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 110/563 - (19%)
• Similarity: 200/563 - (35%)
• Gaps: 196/563 - (34%)

  Fly   190 GAPPTPTVKSIAKQMNITIP------GGGVNPGSPTFSTMGMVAAQKAAASAGGTPLQLRKQLPN 248
            |.|..|.: |..::.::..|      |.|:: ..|.|.....                 .::.|.
 Worm    37 GIPAVPFL-SFLRERDVFCPVFERFHGNGMS-RCPVFWVFSR-----------------EREFPL 82

  Fly   249 PHLHHPYGSMGINAASPLI----------------MQHQLHPPPIHSIEQLMLDDRFLSRFFQYF 297
            ....:.||::     :||:                :|::|.|.....|.:::::|.:..|.
 Worm    83 TRFCNFYGTL-----TPLMVIKKTACYIYRGLFDNVQYELDPKSSEKIYEILMNDGWTYRI---- 138

  Fly   298 SPYERRILAQVCIKWRDTLYRSPRYWSGLLPTLQCRELRQMPGCDRGKLYNSLIRRGFHALGLVG 362
               :.:|:.:..:...|  :...|.:.|:|..|:...::.:   ..|||  .||...:..
 Worm   139 ---KEQIIEKFNLITMD--FGKKRLYRGILDILKAMPIQSI---KLGKL--DLIENDYKQ----- 188

  Fly   363 ASDEDALDVVHSFPLASKHVHSLSLRCSSISDRGLETLLDHLQSLFELELAGCNEVTEAGLWACL 427
            .||:.::|:            |:.:: |::||.. ..||.|      |::.| .||.... |
 Worm   189 RSDKSSIDI------------SMLIK-SALSDNS-RALLQH------LDIEG-REVLSIN-W--- 228

  Fly   428 TPRIVSLSLADCINIADEAVGAVAQLLPSLYEFSLQAYHVTDAALGYFSPKQ----SHSLSILRL 488
             ||.:.|                  |||     ||.:.||...:...|...|    ..:|..|.:
 Worm   229 -PRKIGL------------------LLP-----SLASLHVKGRSFFVFEFTQLCRSFPNLISLNI 269

  Fly   489 QSCWELTNHGIVNIVHSLPHLTVLSLSGCS-KLTDDGVELIAENLQKLRALDLSWCPRITDA--- 549
            ..    ||...:|.:.:|..|.|||:.... :.|:..:.|.  ||..|:.||:|..|.....
 Worm   270 SG----TNIKNLNGISALKRLEVLSMQFLEIETTEHLINLF--NLSNLKFLDISDIPEYDSCIIV 328

  Fly   550 -----------SLEYIAC---DLNQ--LEELTLDR---------------------CVHITDIGV 577
                       :|:::.|   |:|.  ||::.:..                     ||..||...
 Worm   329 HLYVECGKGLPNLKFMDCTATDINNDLLEKILISHPKLETISAIVTNLHRVSDSGVCVLQTDAID 393

  Fly   578 GYISTMLSLTALFLRWCS-----QVRDF--GLQHLCSMRNLQ----VLSLAGCPLLTSSGLSSLI 631
            ..:::::..:.|.|.:.:     ::||.  ..||..:...|:    ::..:.||:....|:|.||
 Worm   394 SAVTSLIQCSRLNLHYLAEKCFYEIRDLLESGQHFNASEFLRKIINLIETSSCPIRKKHGISYLI 458

  Fly   632 QLRHLQELELT----------------NCPGASHELFDYLKEH 658
            :|...|..:||                ..|    |:.|||.|:
 Worm   459 ELAEHQCQKLTLLEVSILLDTLLNQVLELP----EIDDYLSEN 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32085	NP_729732.1	F-box_FBXL16	283..325	CDD:438899	5/41 (12%)
		leucine-rich repeat	382..406	CDD:275381	7/23 (30%)
		AMN1	383..600	CDD:187754	56/266 (21%)
		leucine-rich repeat	431..456	CDD:275381	3/24 (13%)
		leucine-rich repeat	457..482	CDD:275381	6/28 (21%)
		leucine-rich repeat	483..508	CDD:275381	6/24 (25%)
		leucine-rich repeat	509..534	CDD:275381	8/25 (32%)
		leucine-rich repeat	535..560	CDD:275381	8/41 (20%)
		leucine-rich repeat	561..585	CDD:275381	6/44 (14%)
		leucine-rich repeat	586..610	CDD:275381	6/30 (20%)
		leucine-rich repeat	636..661	CDD:275381	9/39 (23%)
gadr-4	NP_001317764.1	LRR	161..>378	CDD:443914	60/281 (21%)