Protein Alignment CG6071 and Aopep

DIOPT Version :10

• Sequence 1: NP_648488.1
• Gene: CG6071 / 39308
• FlyBaseID: FBgn0036186
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: NP_001276853.1
• Gene: Aopep / 72061
• MGIID: 1919311
• Length: 823
• Species: Mus musculus
• Alignment Length: 557
• Identity: 92/557 - (16%)
• Similarity: 179/557 - (32%)
• Gaps: 160/557 - (28%)

  Fly   159 VFPCFDDPRFRTPYNITLVHDRKYVAL-----SNMPPVEEKPYKEIENYV-----STTF------ 207
            :|||.:.|...:.:..|:.....:|.|     |..|....:.|.....||     ::||
Mouse   281 LFPCQEPPVAMSTWQATVRAAASFVVLMSGENSAKPTPLREGYMSWHYYVTMPMPASTFAIAVGC 345

  Fly   208 ------MGSPP--LATQQVM------------WTLHQLEKV--YSGPAAAGENITVWS--RPHLA 248
                  ..|||  |.|:..:            .|.:.:|..  :...:||.::|..:.  .|...
Mouse   346 WTEMKPKASPPDDLMTEHSLPLSPSEADLRYDNTCNHMEYPCRFQSASAASQDIIPYRVFAPVCL 410

  Fly   249 EKLAK------VPEMTPNLFSKYETLFAYPLPKGADWGGKVDHVVLP-RYTEMYSGQGIMVYGED 306
            |...:      :|..   |.:.:..|..:|.       .::|.:::| .:..:......:::
Mouse   411 EGACQEALLWLIPSC---LSAAHSVLGTHPF-------SRLDILIVPTNFPSLGMASPHIIF--- 462

  Fly   307 IVDSGQNGLESLQET-LAELVARQWNGLLVNLEDSDEEYVRNGINYYL----------------- 353
            :..|...|...|..| |...:|..|.||.:...|..||::..|...:|
Mouse   463 LSQSTLTGTSHLCGTRLCHEIAHSWFGLAIGARDWTEEWLSEGFATHLEDIFWAEAQQLPPHEAL 527

  Fly   354 -----------------------SVQVMAMDKEAYNTTHLSKTRLDVLYHDSLAKVKSIATDVKE 395
                                   .:||:..:||  .|.|:|.:...|:.|..          ..|
Mouse   528 EQQELRACLRWHRLQDELRNSPEGMQVLRPNKE--ETGHVSASGASVVKHGL----------NPE 580

  Fly   396 SGHQKLRKKKMCLLIHMLKVALGDKLFLKGLQEFFKRYANSSASSKELWEEFQRGARRSHQLPTG 460
            .|..::...|...|:..|...||:|::...|::|...:......|::..:........:.:|  |
Mouse   581 KGFMQVHYLKGYFLLRFLTRTLGEKIYFPFLRKFVHLFHGQLILSQDFLQMLLENIPENKRL--G 643

  Fly   461 VSLPTVMESWMKQPGFPLLTVQRDDAKQIVTITQSRYYQKYLDNSSNDCWWVPVAYIVRNLTLPQ 525
            :|:..::..|::..|.|....:                    :..:.||   ..:.:.|.:....
Mouse   644 LSVENIVRDWLECSGIPKALQE--------------------ERKAEDC---SPSRLARQVGSEV 685

  Fly   526 VEWLGCQKNSR-----------DILELSHIANPEDWLLINVD-AAVPLRVFYDSYNLQLISEALR 578
            .:|:...:..|           :.|....|....:|||.... :...|.....:|:|......:|
Mouse   686 AKWIRVNRRPRKRKRGKREVAFEKLSPDQIVLLLEWLLEQKTLSPQTLHCLQQTYHLPEQDAEVR 750

  Fly   579 QDFTQI----------PELSRIQLVDDALSLSWSGRL 605
            ..:.::          .::.|..|.|.|:.:...|.|
Mouse   751 HRWCELVIKHKYTKAYNQVERFLLEDQAMGIYLYGEL 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..472	CDD:472708	70/400 (18%)
		ERAP1_C	550..930	CDD:463368	13/67 (19%)
		SSP160	691..>749	CDD:115579
Aopep	NP_001276853.1	GluZincin	<244..641	CDD:472708	66/384 (17%)
		Nucleolar localization signal. /evidence=ECO:0000269|PubMed:17803194	693..703		1/9 (11%)
		Leuk-A4-hydro_C	710..822	CDD:462686	15/78 (19%)