Protein Alignment CG6071 and Trhde

DIOPT Version :10

• Sequence 1: NP_648488.1
• Gene: CG6071 / 39308
• FlyBaseID: FBgn0036186
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: NP_001102461.1
• Gene: Trhde / 366894
• RGDID: 728895
• Length: 1066
• Species: Rattus norvegicus
• Alignment Length: 980
• Identity: 242/980 - (24%)
• Similarity: 423/980 - (43%)
• Gaps: 157/980 - (16%)

  Fly    22 VKPLRYNLTILTRLGSEDEQNQFEGIVSIDIEATQPTRVIYLNSLNITISRQRTWIYRWASGRKI 86
            :|||.|||.:...:    |...|.|.|:::|.....||.:.|::..:.:.:.:.     |..|..
  Rat   187 LKPLHYNLMLTAFM----ENFTFSGEVNVEIACQNATRYVVLHASRVAVEKVQV-----AEDRAF 242

  Fly    87 GALQIKR--IIKKTSLIKIVIELPLRSGEIYTLNMLFSGNLDRSQQYGYF-AGYYDKTPRVFYSA 148
            ||:.:..  :..:|.::.:|:...|.:...|.|.::::. |..::..|:| :.|.....|.|...
  Rat   243 GAVPVAGFFLYPQTQVLVVVLNRTLDAQRHYNLKIIYNA-LIENELLGFFRSSYVIHGERRFLGV 306

  Fly   149 TRLEPDYAHTVFPCFDDPRFRTPYNITLVHDRKYVALSNMPPVEEKPYKEIENYVSTTFMGSPPL 213
            |:..|.:|...|||||:|.::..:.|::.|...|::|||| |||...::| :.:|:..|..:|.:
  Rat   307 TQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNM-PVETSVFEE-DGWVTDHFSQTPLM 369

  Fly   214 ATQQVMWTLHQLEKVY-SGPAAAGENITVWSRPHLAEKLA--KVPEMTPNLFSKYETLF--AYPL 273
            :|..:.|.:...  .| .....:|..:.:::||....:.:  ....:|..|...||..|  .|.|
  Rat   370 STYYLAWAICNF--TYRETTTKSGVVVRLYARPDAIRRGSGDYALHITKRLIEFYEDYFKVPYSL 432

  Fly   274 PKGADWGGKVDHVVLPR--YTEMYS-GQGIMVYGEDIVDSGQNGLESLQE---TLAELVARQWNG 332
            |       |:|.:.:|:  |..|.: |..|.|....::|...:.:..|.:   .:...:..||.|
  Rat   433 P-------KLDLLAVPKHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHEICHQWFG 490

  Fly   333 LLVNLEDSDEEYVRNGINYYLSVQVMAMDKEAYNTTHLSKTRL--DVLYH----DSLAKVKSI-- 389
            .||.....::.:::.|..:|.  :.:..| ..|.:.::.|.|.  |||:.    |.||....:
  Rat   491 DLVTPVWWEDVWLKEGFAHYF--EFVGTD-YLYPSWNMEKQRFLTDVLHEVMLLDGLASSHPVSQ 552

  Fly   390 ----ATDVKESGHQKLRKKKMCLLIHMLKVALGDKLFLKGLQEFFKRYANSSASSKELWEEFQRG 450
                |||: :.....:..||...||.||...:|..:|.:|||::...:...:|:..:||......
  Rat   553 EVLRATDI-DKVFDWIAYKKGAALIRMLANFMGHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEA 616

  Fly   451 ARRSHQLPTGVSLPTVMESWMKQPGFPLLTVQRD-DAKQIVTITQSRYYQK--------YLDNSS 506
            .:|:.:.   |::..||:.|..|.|:|::|:..: .|:..:.|||..:...        .|.|||
  Rat   617 LKRNGKY---VNIQEVMDQWTLQMGYPVITILGNMTAENRILITQQHFIYDIGAKTKALQLQNSS 678

  Fly   507 NDCWWVPVAYIVRN---LTLPQVEWLGCQKNSRDILELSHIANPEDWLLINVDAAVPLRVFYDSY 568
            . .|.:|:..:|.|   ::...:.|:..:.....|..|    :...|:|.|::.....||.||..
  Rat   679 Y-LWQIPLTIVVGNRSHVSSEAIIWVSNKSEHHRITYL----DKGSWILGNINQTGYFRVNYDLR 738

  Fly   569 NLQLISEALRQDFTQIPELSRIQLVDDALSLSWSGRLPYNVTLNVISYLSNETSVLVWETALLNL 633
            |.:|:.:.|.::...:...:|..|:|||.||:.:|.||.|:.|.:|.|||.|...|.|..|...|
  Rat   739 NWRLLIDQLIRNHEVLSVSNRAGLIDDAFSLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASRAL 803

  Fly   634 EKLQSIMRMTTGFRIFKLYMQKLIEPAFKTTLNSLSTKARTGSEIPINTKSPVTTESSGTTESPD 698
            ..|..::.....:.||..|:.|.:    .||.:.|..        |.|..:....::|...|
  Rat   804 YPLDKLLDRMENYNIFNEYILKQV----ATTYSKLGW--------PKNNFNGSVVQASYQHE--- 853

  Fly   699 TTESPDTAESPDTTESSNTTESPDTTESSDTTESPDTTKSDLSLSAILYRLACQFEIKECLTDAQ 763
                                                    :|....|:  |||.|..|.|   .|
  Rat   854 ----------------------------------------ELRREVIM--LACSFGNKHC---HQ 873

  Fly   764 QRFQAAMDQKSS--SSIPEEIREIVLCRGIRNGLEVHWIMVRDMFFESENDKERSILLNSLSCTT 826
            |......|..||  :.||..:|:||.|.|:....|..|..:...|..:....|:.|||.:|:|:.
  Rat   874 QASTLISDWISSNRNRIPLNVRDIVYCTGVSLLDEDVWEFIWMKFHSTTAVSEKKILLEALTCSD 938

  Fly   827 EYWAMQKLLSWALDSKKVPRTMTASLLSAVLRSPLGYYVGKQFLIDHSKEILRSK-------DVK 884
            :...:.:||:.:|:|:.|.......::..|.|:|.|..:..:|..|..| ||.::       :.|
  Rat   939 DRNLLSRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFRDKWK-ILNTRYGEALFMNSK 1002

  Fly   885 LI--LTPFINAMSTKAEFSALNDHL--HRNLPSSMVSGLSSTLESGLDRVNWRNNLYFDLL---- 941
            ||  :|.|:|   |:.|...|.:.:  :..:.|:..|....|:|:   .|.|: .||.|.|
  Rat  1003 LISGVTEFLN---TEGELKELKNFMKSYDGVASASFSRAVETVEA---NVRWK-RLYQDELFQWL 1060

  Fly   942 -KAIR 945
             ||:|
  Rat  1061 GKAMR 1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..472	CDD:472708	113/472 (24%)
		ERAP1_C	550..930	CDD:463368	99/392 (25%)
		SSP160	691..>749	CDD:115579	4/57 (7%)
Trhde	NP_001102461.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	117..177
		M1_APN-Q_like	190..635	CDD:341064	113/472 (24%)
		ERAP1_C	720..1044	CDD:463368	98/387 (25%)