Protein Alignment CG6071 and AgaP_AGAP003692

DIOPT Version :9

• Sequence 1: NP_648488.1
• Gene: CG6071 / 39308
• FlyBaseID: FBgn0036186
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: XP_562562.2
• Gene: AgaP_AGAP003692 / 3290884
• VectorBaseID: AGAP003692
• Length: 932
• Species: Anopheles gambiae
• Alignment Length: 1006
• Identity: 219/1006 - (21%)
• Similarity: 371/1006 - (36%)
• Gaps: 254/1006 - (25%)

  Fly    13 LSAKLAESFVKPLRYNLTILTRLGSEDEQN----QFEGIVSIDIEATQPTRVIYLNSLNITISRQ 73
            |..|::|    |:.|||.:       |..|    .:.|.|.|....|......||||..:.|:.:
Mosquito    41 LLPKVSE----PINYNLFL-------DITNYDFYSYNGTVEITFRYTGDQNHFYLNSDGLVIATE 94

  Fly    74 RTWIYRWASGRKIGALQIKRIIKKTSLIKIVIEL--PLRSGEIYTLNMLFSGNLDRSQQYGYFAG 136
            ...:    :|.....:.:..:|......:|....  .|::.|.|.:.:.|..|:....:..|.:.
Mosquito    95 SIKV----TGPDGTDVPVANVIYMEEFEQIYFGFRDRLQTREQYKIAISFLNNIGTELKGLYRSS 155

  Fly   137 YYDKTPRVFYSATRLEPDYAHTVFPCFDDPRFRTPYNITLVHDRKYVALSNMPPVEEKPYKEIEN 201
            |.......:.:.|..|..||.:||||:|:|.::..:|:.:.|..:|.||||||.:..   ..:.:
Mosquito   156 YMAGNTTRYLATTHFESTYARSVFPCYDEPSYKATFNVKIRHRSEYRALSNMPAINS---VTVGD 217

  Fly   202 YVSTTFMGSPPLATQQVMWTLHQLEKVYSGPAAAGENITVWSRPHLAEKLAKVPEMTPNLFSKYE 266
            |..|||..:|.::|..:.:.:...:.:    :...:...|::............|...|.....|
Mosquito   218 YTETTFDTTPLMSTYLLAFVISDFKTL----SHESDRFRVFAAESKVAHTGYALEFLGNSLRTLE 278

  Fly   267 TLFA--YPLPK-----------GA--DWGGKVDHVVLPRYTEMYSGQGIMVYGEDIVDSGQNGLE 316
            ..|.  |.|||           ||  :||       |..:.|.|     ::|.|.:..:
Mosquito   279 NFFGRQYQLPKVDLIAIPDFAMGAMENWG-------LITFREQY-----LIYEEGVTTA------ 325

  Fly   317 SLQETLAELVARQ----WNGLLVNLEDSDEEYVRNG----INYYLSVQVMAMDKEAY-------- 365
            ..::.:|:|:..:    |.|..|..|.....::..|    ..||::.|||......|
Mosquito   326 RTKQNIADLITHELTHMWFGNEVTPEWWTYLWLSEGFARYFEYYITSQVMNQIFVKYVIVPHVFC 390

  Fly   366 NTTHLSKTRLDVLYHDSLAKVKSIATDVKESGHQKLRKKKMCLLIHMLKVALGDKLFLKGLQEFF 430
            :||          :..||...         ||.:.:....:          :|...|.:.|.::.
Mosquito   391 STT----------FSSSLPGT---------SGSKFIVNNNV----------IGFDTFRQSLNDYL 426

  Fly   431 KRYANSSASSKELWEEFQRGARRSHQLPTGVSLPTVMESWMKQPGFPLLTVQRDDAKQIVTITQS 495
            :..:..:...:.|:...::  .|:..||..:.|  :.|||...||:|::||..|..|:.:|.:|.
Mosquito   427 RSRSYLTTRPQYLYTSIEK--FRTVDLPASIEL--IFESWANTPGYPVVTVSIDRTKRTLTASQK 487

  Fly   496 RYYQ-KYLDN-SSNDCWWVPVAYIVRNLTLPQVE------WLGCQKNSRDI-LELSHIANPEDWL 551
            |::. ..||. ..|..:::||.|.....|....|      ||..|..:..: ||..     .:|:
Mosquito   488 RFWMPNELDTPPQNMLFYIPVNYGTNVPTSTNFEDTTPTFWLTPQDPTATVSLEAG-----VEWV 547

  Fly   552 LINVDAAVPLRVFYDSYNLQLISEAL--RQDFTQIPELSRIQLVDDALSLSWSGRLPYNVTLNVI 614
            ::|.......||.||..:...:.|.|  .|...|:|.::|.|||||..:|:.:|.:.|:|.|:::
Mosquito   548 VVNKQQTGYYRVNYDDESWHKLIEVLNSEQFEDQLPVINRAQLVDDVANLARAGEVGYDVALSLM 612

  Fly   615 SYLSNETSVLVWET---ALLNLEKL----------QSIMRMTTGFRIFKLYMQKLIEPAFKTTLN 666
            .||..||..:.|.|   |||:|:::          ::.:|..||.    :|...|:
Mosquito   613 QYLERETEYIPWATAYNALLHLDRMFSSHEEYSRFETFLRTITGC----MYENILL--------- 664

  Fly   667 SLSTKARTGSEIPINTKSPVTTESSGTTESPDTTESPDTAESPDTTESSNTTESPDTTESSDTTE 731
                   ||
Mosquito   665 -------TG-------------------------------------------------------- 666

  Fly   732 SPDTTKSDLSLSAILYRLACQFEIKECLTDAQQRFQAAMDQKSSSSIPEEIREIVLCRGIRNGLE 796
             |....|.|.....:| |||...:|:||.||......|: |.||.:||||::..|.|       .
Mosquito   667 -PMDQISRLHRGNTVY-LACYSGVKKCLDDAHALANKAV-QDSSFTIPEEVQASVFC-------A 721

  Fly   797 VH-----WIMVRDMFFE----SENDKERSILLN----SLSCTTEYWAMQKLLSWALDSKKVP-RT 847
            :|     .:.|:...||    |.|..|...::|    |:.|......|:..|:  |.:...| ..
Mosquito   722 LHKYPSATLNVQTDLFEKYVTSANSPEDLDMINRFLASVGCARNETIMEYYLT--LSAYNYPGLP 784

  Fly   848 MTAS-----LLSAVLRSPLGYYVGKQFLIDHSKEI---LRSKDVKLILTPFINAMSTKAEFSALN 904
            :||.     .|..:..||.......|:|.:|...:   |.|  |..|.|...|.::|:.:...|.
Mosquito   785 VTAGQRSQIYLGLINGSPGTRQAALQYLYEHFSTVTYLLTS--VTPIFTELGNRINTRLQHEVLK 847

  Fly   905 ---DHLHRNLPSSMVSGLSSTLESGLDRVNW 932
               |.....|.::..:...:.|......:.|
Mosquito   848 NIVDEYGHMLTTAAKAAADAALVKAEQNIRW 878

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..477	CDD:301352	99/488 (20%)
		ERAP1_C	551..929	CDD:288671	93/417 (22%)
AgaP_AGAP003692	XP_562562.2	Peptidase_M1	42..374	CDD:279741	79/371 (21%)
		M1_APN_2	49..469	CDD:189008	99/488 (20%)
		ERAP1_C	547..>819	CDD:288671	82/359 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920