Protein Alignment CG6071 and LOC11175889

DIOPT Version :10

• Sequence 1: NP_648488.1
• Gene: CG6071 / 39308
• FlyBaseID: FBgn0036186
• Length: 962
• Species: Drosophila melanogaster
• Sequence 2: XP_003436573.2
• Gene: LOC11175889 / 11175889
• VectorBaseID: AGAMI1_012506
• Length: 935
• Species: Anopheles gambiae
• Alignment Length: 989
• Identity: 198/989 - (20%)
• Similarity: 365/989 - (36%)
• Gaps: 213/989 - (21%)

  Fly    22 VKPLRYNLTILTRLGSEDEQNQ--FEGIVSIDIEATQPTRVIYLNSLNITISRQRTWIYRWASGR 84
            |.|..|::.|...|..|..:.|  |:|...|.: :||..     |.:.|.:...|..|..|:..|
Mosquito    51 VWPTHYDIEIKPYLEQEGNKAQFTFDGSAKITV-STQKQ-----NVMQIKLHMARMDITAWSVTR 109

  Fly    85 KIGALQIKRI----IKKTSLIKIVIELPLRSGEIYTLNMLFSGNLDRSQQYGYFAGYY-DKTPRV 144
            |.....|..:    .::|.::.:.:...|::...|.|:..:.||:| ...:|::..|| :...:|
Mosquito   110 KSDNTIIPTLPQTYDQETQILTLPLSSALQANVEYVLSFTYVGNMD-DDMHGFYRSYYWEDGVKV 173

  Fly   145 FYSATRLEPDYAHTVFPCFDDPRFRTPYNITLVHDRKYVALSNMPPVEEKPYKEIENYVSTTFMG 209
            :..:|:.:..:|...|||||:|||:..:.:.:.|..:|...|| ..:......|:...: |||..
Mosquito   174 WMGSTQFQQTHARRAFPCFDEPRFKATFQLKINHKTQYNVYSN-TAIVGTAVAEVGRTL-TTFGV 236

  Fly   210 SPPLATQQVMWTL--HQLEKVYSGPAAAGENITVWSRPHLAEKLAKVPEMTPNLFSKYETLFAYP 272
            :|.:::..:.:.:  :|:..        .:.:.:.:||....:.....::...|....|....||
Mosquito   237 TPSMSSYLIAFIVAPYQIND--------RDGMGILARPQAQNQTQYSLDVGIKLLKALEEWIDYP 293

  Fly   273 LPKGADWGGKVDHVVLPRYTEMY------------SGQGIMVYGEDIVDSGQNGLESLQE----- 320
                        :..:...|.||            ...|::.|.|..:....:...|:|:
Mosquito   294 ------------YASVAGMTRMYMAAVPDFSAGAMENWGLLTYRETNILYRSDDSTSMQQHRIAA 346

  Fly   321 TLAELVARQWNGLLVNLEDSDEEYVRNGINYYLSVQVMAMDKEAYNTTH--LSKTRLDVLYHDSL 383
            .::..:|.||.|.||..|..|..::..|...|......|:.:..:|..|  :.:....|:..|||
Mosquito   347 VISHEIAHQWFGDLVTCEWWDVTWLNEGFARYYQYYGTALVETEWNLDHQFVVEQLQGVMQMDSL 411

  Fly   384 AK----VKSIATDVKESG-HQKLRKKKMCLLIHMLKVALGDKLFLKGLQEFFKRYANSSASSKEL 443
            ..    ...:.|..:.|| ...:...|..:::.|::..|..:.|...|:.:.|..|..:...::|
Mosquito   412 RSTHPMTHPVYTQAQASGIFDNISYNKGAVMLRMMEHYLTTETFKTALRAYIKDRAFKTTRPEDL 476

  Fly   444 WEEFQR---GARRSHQLPTGVSLPTVMESWMKQPGFPLLTVQRDDAKQIVTITQSRYYQKYLDNS 505
            :....|   .||            :.||.|..|.|:||:||...|..  .||||.|:.....|::
Mosquito   477 FSALNRYDPNAR------------SYMEPWTIQSGYPLVTVTSHDTG--FTITQKRFLVNEPDHN 527

  Fly   506 SNDCWWVPVAYIVR----NLTLP--------QVEWLGCQKNSRDILELSHIANPEDWLLINVDAA 558
            ....|.:|:.:..:    ::|.|        ::...|              |:..::.::|....
Mosquito   528 EQIAWPLPITFATKASEFSITRPAFYTGMTFEIPMQG--------------ASDVEYFILNNQQV 578

  Fly   559 VPLRVFYDSYNLQLISEALRQD-FTQIPELSRIQLVDDALSLSWSGRLPYNVTLNVISYLSNETS 622
            ...||.||:.....||:||..: |..|..|:|.|:|||..:|:....:||...|.::.||..||.
Mosquito   579 GYYRVNYDAILWGKISKALHSEGFGGIHVLNRAQIVDDLFNLARGDVVPYGTALEILEYLKEETE 643

  Fly   623 VLVWETALLNLEKLQSIMRMTTGFRIF----KLYMQKLIEPAFKTTLNSLSTKARTGSEIPINTK 683
            ...|..|:..|..|..        ||.    ||:...::: .|....:.:..:|.|.:|..|.|
Mosquito   644 YAPWLAAVNGLTTLSR--------RIHADDEKLFAAHILD-IFSKAYDIVKFQAPTATERRIFT- 698

  Fly   684 SPVTTESSGTTESPDTTESPDTAESPDTTESSNTTESPDTTESSDTTESPDTTKSDLSLSAILYR 748
                                                                     .:...:.:
Mosquito   699 ---------------------------------------------------------YMRQNVLQ 706

  Fly   749 LACQFEIKECLTDAQQRFQAAMDQKSSSSIPEEIREIVLCRGIRNGLEVHWIMVRDMFFESENDK 813
            .||.:..:||...|...|. ...|..|..:..::|::|.|.|||.|....:..:.:.:..:....
Mosquito   707 WACNYGHEECSKAAVAEFH-RYHQNPSVKVHPDLRQVVYCEGIRKGSTEEFEFLWNQYLTTNVAT 770

  Fly   814 ERSILLNSLSCTTEYWAMQKLLSWALDSKKVPRTMTASLLSAVLRS-----PLGYYVGKQFLIDH 873
            |:.::|..|.|              :.|.::...|...:.|..:||     ...|.:...:.:.|
Mosquito   771 EQILILQGLGC--------------VSSSELITDMLNGIASPHVRSQDKNNAFTYVINNPYTLPH 821

  Fly   874 SKEILRSKDVKLILTPFINAMSTKAEF----SALNDHLHRNLPSSMVSGLSSTLESGLDRVNWRN 934
            ....|:....        |..::...:    ||.|:.|.|....|....:|:.:||   ..|...
Mosquito   822 VSRYLQQNHA--------NWAASHGSYTNVASAFNNVLARLKSDSERDAISAFIES---NKNILG 875

  Fly   935 NLYFDLLKA-IRDF 947
            ...:|.:|: :.|:
Mosquito   876 QAAYDSIKSGLEDY 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6071	NP_648488.1	GluZincin	25..472	CDD:472708	97/482 (20%)
		ERAP1_C	550..930	CDD:463368	76/393 (19%)
		SSP160	691..>749	CDD:115579	0/57 (0%)
LOC11175889	XP_003436573.2	None