Protein Alignment Plod and plod1

DIOPT Version :10

• Sequence 1: NP_648451.1
• Gene: Plod / 39265
• FlyBaseID: FBgn0036147
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001072340.1
• Gene: plod1 / 779793
• XenbaseID: XB-GENE-955414
• Length: 722
• Species: Xenopus tropicalis
• Alignment Length: 729
• Identity: 327/729 - (44%)
• Similarity: 470/729 - (64%)
• Gaps: 29/729 - (3%)

  Fly     8 LLLLLLAVTSQGDAESNWN-DKIKVFTVATEPTDGYTRYIRSARVYDIEVTTLGLGEEWKGGDMQ 71
            |||.:||:..|....:|.: |.:.|.|:|||.|||..|:.|||..::.:|..|||||||.
 Frog     8 LLLGVLAIQPQSMNCANASADNLLVLTIATEETDGLKRFQRSAHSFNYKVKVLGLGEEWL----- 67

  Fly    72 KPGGGFKLNLLREAIAPYKNEPETIILFTDSYDVIITTTLDEIFEKFKESGAKILFSAEKYCWPD 136
              |.|.|:.|::.|:.||.::.:.|||||:|||||..:...|:.:||:::.:|::||||...:||
 Frog    68 --GEGQKVRLMKFALEPYADKEDLIILFTESYDVIFASGPGELLKKFRQAKSKVVFSAESVAYPD 130

  Fly   137 KSLANDYPEVEGKASRFLNSGAFIGYAPQVFALLVD-PIEDTADDQLYFTKIFLDETKRAKLGLK 200
            :.|.:.||.| |:..|||.||||||||..::.::.| ..:|...|||::||:|||..||.|:.:.
 Frog   131 RHLESKYPAV-GEGKRFLGSGAFIGYATHLYKMVADWDGKDKDSDQLFYTKLFLDPVKRGKINIT 194

  Fly   201 LDVQSRLFQNLHGAKNDVKLKVDLESNQGVLQNVDFMTTPSIIHGNGLSKVDLNAYGNYLAR--T 263
            ||.:.|:||||:|:..||.||  .|:.:...:.:.:.|.|.:|||||.:|:.||..|||:.|  |
 Frog   195 LDHRCRIFQNLYGSAEDVALK--FENGRVRARYLVYDTLPVLIHGNGPTKLHLNYLGNYIPRVWT 257

  Fly   264 FNGVCLLCQENLLDLEETNL---PVISLALMVTQPVPFFDQFLEGIESLNYPKEKLHLLIYSNVA 325
            |...|.:|.|.:.:||...:   |::.:.:.:.||.||..:|.:.:.:|||||:::.|.|.::..
 Frog   258 FESGCNVCDEGVRNLEGLTVDTFPLVVIGIFIEQPTPFVSEFFKRLNNLNYPKKRIQLYISNHEP 322

  Fly   326 FHDDDIKSFVNKHAKEYATAKFALSTDELDERQGRQLALDKAR-LHQSDYIFFVDADAHIDDGEV 389
            .|...:::|:..:..:|:..|.....:..|....|...:|..| ..:.:|.|.:||...:.:..:
 Frog   323 HHQRRVENFLQAYGTQYSFVKTVGPDENSDFADSRNKGMDMCRQTPECEYYFSIDAPVVLKNINI 387

  Fly   390 LRELLRLNKQFVAPIFSKHKELWSNFWGALSEGGYYARSHDYVDIVKRELIGMFNVPHVTSIYLV 454
            ||.|:..||..:||:.|:...||||||||||..||||||.||:.||:|:.||::|||:::|:|||
 Frog   388 LRILIEQNKSVIAPLVSRTANLWSNFWGALSSDGYYARSEDYIHIVQRQRIGVWNVPYISSVYLV 452

  Fly   455 KKTAFDAISFKHKEF-----DPDMAMCESLRNAGIFMYASNLRIFGHLVNADDFNTTVTRPDFYT 514
            |.:...:...::..|     |.|||.|.::|..||||:.:|.:.|||:::.:::.||....|.:.
 Frog   453 KGSILRSKLSQNDIFHSGTQDFDMAFCHNIRQQGIFMFVTNRQEFGHILSLENYKTTHLHNDLWE 517

  Fly   515 LFSNEIDWTEKYIHPNYSLQLNESNKIQQPCPDVYWFQIVSDAFCDDLVAIMEAHNGWSDGSNND 579
            :|.|..||.|||||||:|..| :...::.||||||||.|.|:..|::||..||....||.|||.|
 Frog   518 IFENTEDWKEKYIHPNHSEAL-KGKLVEMPCPDVYWFPIFSETTCNELVEEMENFGKWSSGSNKD 581

  Fly   580 NRLEGGYEAVPTRDIHMKQVGLERLYLKFLQMFVRPLQERAFTGYFHNPPRALMN--FMVRYRPD 642
            |||:||||.|||.||||.|:|.|:.:.|.|..|:.||.|:.|.||:   .||..:  |:|||:||
 Frog   582 NRLQGGYENVPTIDIHMNQIGYEKEWHKILLDFIAPLTEKLFPGYY---TRAQFDLAFVVRYKPD 643

  Fly   643 EQPSLRPHHDSSTYTINIAMNRAGIDYQGGGCRFIRYNCSVTDTKKGWMLMHPGRLTHYHEGLLV 707
            |||.|.||||:||:|||||:|..|.||:||||||:||||||...:|||.||||||||||||||.|
 Frog   644 EQPLLEPHHDASTFTINIALNSVGQDYEGGGCRFLRYNCSVRAPRKGWALMHPGRLTHYHEGLRV 708

  Fly   708 TNGTRYIMISFIDP 721
            |.|||||::||:||
 Frog   709 TKGTRYIVVSFVDP 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Plod	NP_648451.1	GT_LH	27..257	CDD:459235	100/230 (43%)
		Glyco_tranf_GTA_type	303..>395	CDD:472172	22/92 (24%)
		P4Hc	555..719	CDD:214780	102/165 (62%)
plod1	NP_001072340.1	GT_LH	28..249	CDD:459235	100/230 (43%)
		P4Hc	557..720	CDD:214780	102/165 (62%)