DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14142 and mindy4

DIOPT Version :9

Sequence 1:	NP_648447.2	Gene:	CG14142 / 39261	FlyBaseID:	FBgn0036143	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_001072940.1	Gene:	mindy4 / 780771	XenbaseID:	XB-GENE-6456867	Length:	746	Species:	Xenopus tropicalis

Alignment Length:	431	Identity:	115/431 - (26%)
Similarity:	176/431 - (40%)	Gaps:	93/431 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GTPITAELATDLRNLVFGTAAIPMRAEWLQTSFVFGAPKEELAYGLRSPRNATRGLLSVVQGFVL 74
            |.||....|.:::.::||::......||...||.|. ..:.|.||....:....|:|:.|||.||
Frog   396 GKPIDLAQAVEIKKILFGSSFCCFSDEWKIQSFTFN-NNQPLRYGFIQKKGGPCGVLAAVQGCVL 459

  Fly    75 KYLLFARKTSRVASLTDPLLATADMQREALFC-ALLEILRTISDKGKVTMVLPSEDEVFVDHSAC 138
            |.|||.:.    |.|.  :|..:|.||.:..| |:.:||....|..:..:.|......| ..:..
Frog   460 KNLLFGKD----ADLR--VLQPSDSQRTSCLCKAIADILWRAGDNKEAVVALSCGRPQF-SPAGR 517

  Fly   139 YFHDSVTEKLYVFTLSPNDELEYFLKRNFKYFTEEETP-GTLLFLYSAVLTRSMGKVRTDLDSAK 202
            |..|.:.|.|.::.:...::|..|::::...|  |..| |..|...|.||:||:..|:.|.|  .
Frog   518 YKADGILESLILYKIRKYEDLMGFVQQHISQF--ELGPFGCTLLTLSVVLSRSVELVQKDFD--V 578

  Fly   203 STPLTSSNHEEGSLMIVTLLLTGRATPYIHNGVVNVGDESSYAVPQYGVLKRCMIGLL-LWDIES 266
            ||......|...:..:|.|:|:|||...:.|.||.:...:.......||..|..||.| |::..:
Frog   579 STNCLIGAHSYCTQELVNLILSGRAVSNVFNDVVELDSGNGNITLLRGVAHRTDIGFLSLFEHYN 643

  Fly   267 ASAAVNQSRQPGSRLKTPNYPIWITSCTGHFGVIFNKNPDLLRNYHAESRFDVNYYSCSGHQ--- 328
            ..       |.||.||||.:|||:.....||.|:|....:|:.::..|.|||:.||....:|
Frog   644 VC-------QVGSYLKTPRFPIWVICSESHFSVLFCVRRELMSDWKMERRFDLYYYDGLANQQDE 701

  Fly   329 ILMTIDN-RTYNEQALVMLERQPITPESTSMSGKEDGGGATSPTTVSGGGGAAAGGGVGGASGGV 392
            |.:|:|. .||.|:
Frog   702 IRLTVDTAATYIEE--------------------------------------------------- 715

  Fly   393 GGAASGASGGNDVVAKEESTLNTPLQRLIRTKWEEATISFH 433
                            :|:.|..||:..|||||:.|.|.::
Frog   716 ----------------QENDLTPPLEHCIRTKWKGAVIDWN 740

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14142	NP_648447.2	DUF4205	22..433	CDD:290609	111/417 (27%)
mindy4	NP_001072940.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	123..179
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	198..254
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	319..342
		DUF4205	408..741	CDD:372796	111/419 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	156	1.000	Domainoid score	I4135
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276386at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm49326
Panther	1	1.100	-	-	LDO	PTHR12473
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	1	1.000	-	-		X6307
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.050