DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14142 and aqp4

DIOPT Version :9

Sequence 1:	NP_648447.2	Gene:	CG14142 / 39261	FlyBaseID:	FBgn0036143	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	NP_001345242.1	Gene:	aqp4 / 445293	ZFINID:	ZDB-GENE-040724-152	Length:	346	Species:	Danio rerio

Alignment Length:	193	Identity:	40/193 - (20%)
Similarity:	71/193 - (36%)	Gaps:	52/193 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 LTSSNHE--EGSLMIVTLLLTGRATPYIHNGVVNVGDESSYAV-----PQYGVLK---RCMIGLL 260
            :||.|.|  .|..:::.|::|               .|..:.|     |:...||   ...|||.
Zfish   149 VTSVNEEISAGHAIVIELIIT---------------FELVFTVFATCDPKRNDLKGSAALAIGLS 198

  Fly   261 -----LWDIESASAAVNQSRQPGSRL----KTPNYPIWITSCTGH------FGVIFNKNPDLLRN 310
                 |:.|....|::|.:|..|..:    ...::..|:....|.      :..:|..:|||.|.
Zfish   199 VCIGHLFAIPYTGASMNPARSFGPAVIMVKWQDHWVYWVGPLIGGILAAAVYEYLFCPDPDLKRR 263

  Fly   311 YH---AESRFDVNYYSCSGHQILMTIDNRTY-NEQALVMLERQPITPESTSMSGKEDGGGATS 369
            |.   ::|.|.:..|        ..:|..:| ::||.:|.::..:.........:|..|...|
Zfish   264 YADVLSKSPFQMEPY--------RVVDTDSYPSDQAQLMAKQAALRVLDLEKKERESTGEVLS 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14142	NP_648447.2	DUF4205	22..433	CDD:290609	40/193 (21%)
aqp4	NP_001345242.1	MIP	32..250	CDD:278651	23/115 (20%)
aqp4	NP_001345242.1	DUF737	<290..>345	CDD:310129	6/29 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030