Protein Alignment: APP-BP1 and UBA6

• Sequence 1: NP_001261699.1
• Gene: APP-BP1
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Sequence 2: NP_060697.4
• Gene: UBA6
• HGNCID: 25581
• Length: 1052
• Species: Homo sapiens
• Alignment Length: 510
• Identity: 101/511 (20%)
• Similarity: 177/511 (35%)
• Gaps: 143/511 (28%)

  Fly     8 SPELSDKSKKYDRQIRLWGEHGQTLLEAATVCLVNVTAVGCETAKGLVLPGIGGFTVADGSTVKE 72
            |.|:.|  ..|.||..:.|:.....:..:.|.|..:..:|.|.||.|||.||...|:.|....:.
Human    36 SVEIDD--ALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQA 98

  Fly    73 EDLGNNFFL--DSSYLGKSKALACMQLLQELNPDVNGDYVDESADFLLANRPNFFDSFDLVIASN 135
            .|||.||||  |.....:::|.|.::.:.||||.|:  ....|..|......:|.|.:..|:
Human    99 WDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVH--VTSSSVPFNETTDLSFLDKYQCVV--- 158

  Fly   136 LNEQTLLLLAERLWELNVPLIYCRSLGMLGTIRLQIREHCIVEAHPDNRQFDLRLEHPFDALREH 200
                        |.|:.:||            :.:|.:.|..:..|..          |.:...|
Human   159 ------------LTEMKLPL------------QKKINDFCRSQCPPIK----------FISADVH 189

  Fly   201 LDGTEVTSKVPWLLVLHKYLNVWQKQQADGTQTPRNYKEKNQLKETIREEMKADEENYEEAIKAV 265
                                .:|.:...|       :.::.::.:|..||.|   |.:...|...
Human   190 --------------------GIWSRLFCD-------FGDEFEVLDTTGEEPK---EIFISNITQA 224

  Fly   266 NTAFGAGQVPKSLKAIFEDDACEQLNKKSNVFWIMAKALKHFVIHENEGHLPLPGVLPDMTANTD 330
            |        |..:..:                             ||..|          ...|.
Human   225 N--------PGIVTCL-----------------------------ENHPH----------KLETG 242

  Fly   331 SYIALQHIYRQQALQDADQVYHKCQEYLKQLALPAD---SIDERSVRLICKEAAGLAVIRGTRIA 392
            .::..:.|.....|..:          ::|:.:.:.   ||.: :..|......|:||...|...
Human   243 QFLTFREINGMTGLNGS----------IQQITVISPFSFSIGD-TTELEPYLHGGIAVQVKTPKT 296

  Fly   393 EEYEKSSRLLP-----LVEDNELQGNLTAYNFALRAYERFLSECGNIPG-ECIVEQDIGRLKSIA 451
            ..:|...|.|.     :|:.:..:..|..:. |:.|.::|..:....|. .|  :||...|..:|
Human   297 VFFESLERQLKHPKCLIVDFSNPEAPLEIHT-AMLALDQFQEKYSRKPNVGC--QQDSEELLKLA 358

  Fly   452 AKMLSDLGMHATISDDVLHEICRYGGAELHAVSAFIGGCAAQEVIKIITKQYKPI 506
            ..:...|.....::.|::|.:.......|..::|.:||.|:|||:|.:|.::.|:
Human   359 TSISETLEEKPDVNADIVHWLSWTAQGFLSPLAAAVGGVASQEVLKAVTGKFSPL 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
APP-BP1	NP_001261699.1	APPBP1_RUB	16..522	CDD:238770	98/503 (19%)
		ThiF	17..>171	CDD:223552	41/156 (26%)
UBA6	NP_060697.4	Ube1	38..1046	CDD:273603	100/509 (20%)
		Ube1_repeat1	43..432	CDD:238768	98/502 (20%)
		E1_4HB	299..361	CDD:292809	14/65 (22%)
		Ube1_repeat2	462..1005	CDD:238767

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900