Protein Alignment simj and Gatad2a

DIOPT Version :10

• Sequence 1: NP_001261685.1
• Gene: simj / 39212
• FlyBaseID: FBgn0010762
• Length: 937
• Species: Drosophila melanogaster
• Sequence 2: NP_001423704.1
• Gene: Gatad2a / 290669
• RGDID: 1310596
• Length: 633
• Species: Rattus norvegicus
• Alignment Length: 630
• Identity: 198/630 - (31%)
• Similarity: 275/630 - (43%)
• Gaps: 133/630 - (21%)

  Fly   111 TGATSGSIGGGQDENKVQRRVLRPRTEPKSYAEAPDIVLLPARTNGRQQNGNIDSETDDEEMPPY 175
            ||:..|.:|.|..:.:.....::....|.|    ||:::|                 .|.|.|..
  Rat    67 TGSGEGLLGDGPVDMRTSHSDMKSEKRPPS----PDVIVL-----------------SDSEQPSS 110

  Fly   176 VPIKELSHAELK-------------EREKSLRKLRQDLRNEETKLMLLKKLKQSQQVMKENLVVT 227
            ..:..|:...||             |||:.:::|:::||.||.||:|||||:|| |:.||.....
  Rat   111 PRVNGLTTVALKDTSTEALLKSSPEERERMIKQLKEELRLEEAKLVLLKKLRQS-QIQKEATAQK 174

  Fly   228 PTSVSPNNPLSAIPAALTSKGSLSVTPTSAVPLPAHSKGSRSSLSGSGG--PAVSISATNSRTGS 290
            ||:               |.||...||...|..|.:....:.||..|..  |...|.....|.|.
  Rat   175 PTA---------------SSGSTVTTPPPLVRGPQNIPAGKPSLQTSSTRIPGSIIPPPLVRGGQ 224

  Fly   291 SSSAAAAASAIAAAAMSGQHRSGSNSILPPPRSSLPAGATLAAGTTITPATSS--SHRSSNLPPR 353
            ..||.....|             |:.::.||         |..|..::....:  .|.|:..||.
  Rat   225 QVSAKLGPQA-------------SSQVVMPP---------LVRGAQVSQQIHNIRQHSSTGPPPL 267

  Fly   354 TNLPNLTITPSVTITPTSAPPSSL-KPRNVPGTISNSVSITPALPLSQSHQNQHNDQKNDRSTPR 417
            ...|..:: ||:.|.........| :..|||.|   |:.:....|.:.|.:..........|||.
  Rat   268 LLAPRASV-PSMQIQGQRIIQQGLIRVANVPNT---SLLVNIPQPTAASLKGTTVGSAQANSTPS 328

  Fly   418 E------DAQTPAQRQAAAKMALRKQLEKTLLQIPPPKPPPPEMHFIPNPSNTDFVYLLGLETVV 476
            .      .|::||.||||||:|||||||||||:|||||||.|||:|:|:.:|.:|:||:|||.||
  Rat   329 SVASVVASAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVV 393

  Fly   477 DYLTVNK----KANAVAA-----PFRCAQCKIDFTPVWKWEKQTNKDPKVICEQCVTSNVKKALK 532
            ..|...:    .|.:.||     |:.|.|||.|||..|:     .|...|:||.|:|||.|||||
  Rat   394 QNLLETQAGRISATSAAAVLSREPYMCVQCKTDFTCRWR-----EKGGAVMCENCMTSNQKKALK 453

  Fly   533 AEHTNRLKQAFVKALQQEQEIEQRLASQSSPSPVDNHGSSGGGNSLSVSAVSSNSSSSHMQRERE 597
            .|||:|||.|||||||||||:||||..|             |..:.|:.|.::....|..|..:.
  Rat   454 VEHTSRLKAAFVKALQQEQEMEQRLLQQ-------------GVGTASIKAETAAPHPSLKQVIKP 505

  Fly   598 QLQASHASAAAALVNLPPSVTVIPTKCQTP--TPATPR------PTPPPPQ--SQATPPPSSGGS 652
            :.:.:..|..|...|   :.:|:.|..|..  :..|||      ...|..|  :.||...|..|.
  Rat   506 RRKLAFRSGEARDWN---NGSVLQTSSQLSRGSATTPRGVLHTFSQSPKLQNAASATALVSRTGR 567

  Fly   653 RSSRAAATAAAAAIAAQQAGILSPG------PSPAHHHEPTTSSR 691
            .|.|...|:...|...::..:.:.|      ||.|.|...:...|
  Rat   568 HSERVVGTSKGTASNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDR 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
simj	NP_001261685.1	P66_CC	185..225	CDD:465178	22/52 (42%)
Gatad2a	NP_001423704.1	P66_CC	133..172	CDD:465178	20/39 (51%)
		ZnF_GATA	420..453	CDD:453031	19/37 (51%)