Protein Alignment CG32066 and CYRIB

DIOPT Version :10

• Sequence 1: NP_729619.1
• Gene: CG32066 / 39206
• FlyBaseID: FBgn0052066
• Length: 324
• Species: Drosophila melanogaster
• Sequence 2: XP_011515423.2
• Gene: CYRIB / 51571
• HGNCID: 25216
• Length: 438
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 179/328 - (54%)
• Similarity: 232/328 - (70%)
• Gaps: 11/328 - (3%)

  Fly     1 MGKLLSLLSRDDSNCCAAKSYDVFLDFENAAPTETERAVYDEVERVLRESEVVLDEIQIYRGAGK 65
            ||.||.:|:..|    ..:..:.|||||||.|||:|:.:|::|..||:::|.:|:::|.|||||.
Human   115 MGNLLKVLTCTD----LEQGPNFFLDFENAQPTESEKEIYNQVNVVLKDAEGILEDLQSYRGAGH 175

  Fly    66 EIREAIADPSPE-VTAKAWAAVLPLVNKLKRCYEHSMELDKIVPKLLGQLVGGKLNPTQHLETQQ 129
            ||||||..|:.| :..|||.||:|||.|||:.||.|..|:..:..|||.|.....:||||||.:|
Human   176 EIREAIQHPADEKLQEKAWGAVVPLVGKLKKFYEFSQRLEAALRGLLGALTSTPYSPTQHLEREQ 240

  Fly   130 ALVKQLAEILEFVLKFDEYKMKTPAIQNDFSYYRRIVSRQRVDST----ENMLVSTELANRMSLF 190
            ||.||.||||.|.|:|||.||..||||||||||||.:||.|:::.    ||. |:.|||||||||
Human   241 ALAKQFAEILHFTLRFDELKMTNPAIQNDFSYYRRTLSRMRINNVPAEGENE-VNNELANRMSLF 304

  Fly   191 YAHATPMLKVLSEATSKFVNDNAD-DVQNTTETLGTMAKVCLRMLENPKLLQQIEREDTKMLVLR 254
            ||.||||||.||:||:|||::|.: .::|||:.|.|||.||..|||.|:...:...|:|....||
Human   305 YAEATPMLKTLSDATTKFVSENKNLPIENTTDCLSTMASVCRVMLETPEYRSRFTNEETVSFCLR 369

  Fly   255 VMVGLVILYDHVHPEGAFVRGAHVDVKGCVRLLQAQPAIKAEPLLNALRYTTKHLNGENTPKNIQ 319
            ||||::||||||||.|||.:.:.:|:|||:::|:.||....|.|||||||||||||.|.|.|.|:
Human   370 VMVGVIILYDHVHPVGAFAKTSKIDMKGCIKVLKDQPPNSVEGLLNALRYTTKHLNDETTSKQIK 434

  Fly   320 RLL 322
            .:|
Human   435 SML 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32066	NP_729619.1	CYRIA-B_Rac1-bd	22..319	CDD:462106	171/302 (57%)
CYRIB	XP_011515423.2	CYRIA-B_Rac1-bd	132..434	CDD:462106	171/302 (57%)