Protein Alignment Gem3 and Ddx39a

DIOPT Version :10

• Sequence 1: NP_524019.1
• Gene: Gem3 / 39195
• FlyBaseID: FBgn0011802
• Length: 1028
• Species: Drosophila melanogaster
• Sequence 2: NP_932099.2
• Gene: Ddx39a / 68278
• MGIID: 1915528
• Length: 427
• Species: Mus musculus
• Alignment Length: 424
• Identity: 127/424 - (29%)
• Similarity: 208/424 - (49%)
• Gaps: 31/424 - (7%)

  Fly     2 EREIAHSLAGGEERSSDVAPGQ---------VK---------TFEELRLYRNLLNGLKRNNFVTP 48
            |:::.:.|...:|.....||.:         ||         .|.:..|...||..:....|..|
Mouse     3 EQDVENELLDYDEDEEPQAPQESTPAPPKKDVKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHP 67

  Fly    49 TKIQAAAIPMALAKMDLIIQSKSGTGKTLIYVIAVVQSFNPNINQPHAMIVVPTRELAIQVQDTF 113
            :::|...||.|:..||::.|:|||.|||.::|:|.:|...|...|...:::..|||||.|:...:
Mouse    68 SEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVSVLVMCHTRELAFQISKEY 132

  Fly   114 FHLCKSFRDFKCSAFIGGTDVAKDRK--RMNESRVIIGTPGRLLHLYENRVFDVSKLRLLVLDEA 176
            ....|.....|.|.|.||..:.||..  :.|...|::|||||:|.|..:|..::..::..||||.
Mouse   133 ERFSKYMPSVKVSVFFGGLSIKKDEDVLKKNCPHVVVGTPGRILALVRSRSLNLRNVKHFVLDEC 197

  Fly   177 DQLYQTKSLQHTVSKLIEAMPKNRQIIACSATYDQNLDERLAKVMDKPM-LISNSERATVLLGIR 240
            |::.:...::..|.::....|..:|.:..|||..:.:.....|.|..|| :..:.|....|.|::
Mouse   198 DKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKEIRPVCRKFMQDPMEVFVDDETKLTLHGLQ 262

  Fly   241 QFVYELPQQNNSVEEMRLKLQILGQIFNQLPYEQAIIFASSQMRADSYKNYLTASGIDCHLISGA 305
            |:..:|....        |.:.|..:.:.|.:.|.:||..|..|..:....|.........|...
Mouse   263 QYYVKLKDSE--------KNRKLFDLLDVLEFNQVVIFVKSVQRCMALAQLLVEQNFPAIAIHRG 319

  Fly   306 MEQSERLHVFEGYRNFTMRILVATDLMARGVDSPHANLVINIDPPQDHVTYLHRIGRAGRFGSKG 370
            |.|.|||..::.:::|..||||||:|..||:|....|:|.|.|.|:|..|||||:.||||||:||
Mouse   320 MAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKG 384

  Fly   371 IAITFIASKKESQRFREMSKKIATAWSVLEFPKE 404
            :|:||::.:.:::...::..:...  :|.|.|:|
Mouse   385 LAVTFVSDENDAKILNDVQDRFEV--NVAELPEE 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gem3	NP_524019.1	SrmB	26..409	CDD:440279	120/382 (31%)
Ddx39a	NP_932099.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		6/32 (19%)
		DEADc_DDX39	43..250	CDD:350708	63/206 (31%)
		Q motif	44..72		6/27 (22%)
		DECD box	195..198		2/2 (100%)
		SF2_C_DEAD	261..390	CDD:350174	49/136 (36%)