Protein Alignment Gem3 and Eif4a3l1

DIOPT Version :10

• Sequence 1: NP_524019.1
• Gene: Gem3 / 39195
• FlyBaseID: FBgn0011802
• Length: 1028
• Species: Drosophila melanogaster
• Sequence 2: NP_001136206.1
• Gene: Eif4a3l1 / 668137
• MGIID: 3644226
• Length: 411
• Species: Mus musculus
• Alignment Length: 423
• Identity: 127/423 - (30%)
• Similarity: 207/423 - (48%)
• Gaps: 49/423 - (11%)

  Fly    18 DVAPGQVKTFEELRLYRNLLNGLKRNNFVTPTKIQAAAIPMALAKMDLIIQSKSGTGKTLIYVIA 82
            |..|    ||:.:.|..:||.|:....|..|:.||..||...:...|:|.||:||||||..:.|:
Mouse    35 DATP----TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSIS 95

  Fly    83 VVQSFNPNINQPHAMIVVPTRELAIQVQDTFFHLCKSFRDFKCSAFIGGTDVAKDRKRMNESR-V 146
            |:|..:..:.:..|:|:.||||||:|:|.....| ..:.:.:|.|.:|||:|.:|.::::..: |
Mouse    96 VLQCLDIQVRETQALILAPTRELAVQIQKGLLAL-GDYMNVQCHACVGGTNVGEDIRKLDYGQHV 159

  Fly   147 IIGTPGRLLHLYENRVFDVSKLRLLVLDEADQLYQTKSLQHTVSKLIEAMPKNRQIIACSATYDQ 211
            :.|||||:..:...|......:::|||||||::. .:..:..:..:...:|...|::..|||...
Mouse   160 VAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEML-NRGFKEQIYDVYRYLPPATQVVLVSATLPH 223

  Fly   212 NLDERLAKVMDKPMLISNSERATVLLGIRQFVYELPQQNNSVEEMRLKLQILGQIFNQLPYEQAI 276
            .:.|...|.|..|:.|........|.||:||..       :||....|...|..:::.|...||:
Mouse   224 EILEMTNKFMTHPIRILVKRDELTLEGIKQFFV-------AVEREEWKFDTLCDLYDTLTITQAV 281

  Fly   277 IFASSQMRADSYKNYLTASGIDCHLISGAMEQSERLHVFEGYRNFTMRILVATDLMARGVDSPHA 341
            ||..::.:.|.....:..:......:.|.|.|.||..:.:.:|:...|:|::||:.|||:|.|..
Mouse   282 IFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQV 346

  Fly   342 NLVINIDPPQDHVTYLHRIGRAGRFGSKGIAITFIASKKESQRFREMSKKIATAWSVLEFPKEPM 406
            :|:||.|.|.:...|:|||||:||:|.||:||.|:  |.:..|...
Mouse   347 SLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFV--KNDDIRILR------------------- 390

  Fly   407 PNEFNFWDFEKYNFDYYIKEENPLQEMPMPIKE 439
                   |.|:|       ....:.||||.:.:
Mouse   391 -------DIEQY-------YSTQIDEMPMNLAD 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gem3	NP_524019.1	SrmB	26..409	CDD:440279	118/383 (31%)
Eif4a3l1	NP_001136206.1	DEAD-like_helicase_N	22..411	CDD:475120	127/423 (30%)