Protein Alignment Gem3 and ais

DIOPT Version :10

• Sequence 1: NP_524019.1
• Gene: Gem3 / 39195
• FlyBaseID: FBgn0011802
• Length: 1028
• Species: Drosophila melanogaster
• Sequence 2: NP_649009.1
• Gene: ais / 39979
• FlyBaseID: FBgn0036754
• Length: 594
• Species: Drosophila melanogaster
• Alignment Length: 571
• Identity: 140/571 - (24%)
• Similarity: 236/571 - (41%)
• Gaps: 141/571 - (24%)

  Fly    21 PGQVKTFEEL--------RLYRNLLNGLKRNNFVTPTKIQAAAIPMALAKMDLIIQSKSGTGKTL 77
            |..|.:|..|        ||.:|||:    .||..||.||..|:|:.|.:..|:..:.:|:||||
  Fly   111 PPPVDSFGTLTRDFKMLPRLQQNLLS----RNFDHPTPIQMQALPVLLQRRALMACAPTGSGKTL 171

  Fly    78 IYVIAVVQSFNPN-INQPHAMIVVPTRELAIQVQDTFFHLCKSFRDFKCSA----------FIGG 131
            .::..::.....: .....|:::.||||||.|:          :|:  |:.          ||..
  Fly   172 AFLTPIINGLRAHKTTGLRALVLAPTRELAQQI----------YRE--CAELTRETGLRTHFISK 224

  Fly   132 TDVAKDRKRMNESR----VIIGTPGRLLHLYENR--VFDVSKLRLLVLDEADQLYQ--TKSLQHT 188
            ...|| :|...|.:    :::.||.|:..|.:..  :.|:|.:...||||||:|.:  ..:.:..
  Fly   225 VSEAK-QKHGAECKQRYDILVSTPNRVRFLLQQEPPLLDLSHVEWFVLDEADRLMEEGQNNFKEQ 288

  Fly   189 VSKLIEAMPKNRQIIA-CSATYDQNLDERLAKVMDKPMLISNSERATVLLGIRQFVYELPQQNNS 252
            :..:..|.....:.:| .||||...:.:...:      .:.|..|.|:  |:         ||::
  Fly   289 LDDIYAACSNPTKCVAFFSATYTVPVAKWALR------HLKNLVRITI--GV---------QNSA 336

  Fly   253 VEEMRLKLQILG----------QIFNQLPYEQAIIFASSQMRADSYKNYLTASGIDCHLISGAME 307
            .|.::.:|..:|          .:..|......::|..|:.||......|...||:..:|.....
  Fly   337 TETVQQELLFVGSEGGKLVAIRDLVRQGLQPPVLVFVQSKERAKQLFEELLYDGINVDVIHAERS 401

  Fly   308 QSERLHVFEGYRNFTMRILVATDLMARGVDSPHANLVINIDPPQDHVTYLHRIGRAGRFGSKGIA 372
            |.:|.:..:.:|..::.:|:.|:||.||:|....|||||.|.|...::|:|||||.||.|..|.|
  Fly   402 QHQRDNCVKAFREGSIWVLICTELMGRGIDFKGVNLVINYDFPPTTISYIHRIGRTGRAGRPGRA 466

  Fly   373 ITFIASKKESQRFREMSKKIATAWSVLEFPKEPMPNEFNFWDFEKYNFDYYIKEENPLQEMPMPI 437
            |||                         |.:|...|                     |:.:.:.|
  Fly   467 ITF-------------------------FTQEDTSN---------------------LRGIALII 485

  Fly   438 KENRSKENVDASSVDLENLQKDQDGKRRDPDKLPVALENVETQKELELENLPESSHNNKNLRVKE 502
            |  .|...|....:.::.::|.:...|.   |.|:..|::.|:..      ||:..:.|:...|.
  Fly   486 K--NSGGTVPEYMLQMKKVRKSEAKMRA---KKPLDREDISTKIR------PETKGDEKHKSTKL 539

  Fly   503 KEIVRQGKL--------KETNS---KAGGSKTN-KTERRKKSNTPSKLQKQ 541
            |::.|..|:        |:.||   |.|..||. |...::|.|...|.:.:
  Fly   540 KKVERTEKILKNRKGYEKDLNSKQKKLGNIKTELKPAGKRKGNVEKKTKNK 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gem3	NP_524019.1	SrmB	26..409	CDD:440279	108/420 (26%)
ais	NP_649009.1	SrmB	123..538	CDD:440279	121/505 (24%)