Protein Alignment Gem3 and eIF4A

DIOPT Version :10

• Sequence 1: NP_524019.1
• Gene: Gem3 / 39195
• FlyBaseID: FBgn0011802
• Length: 1028
• Species: Drosophila melanogaster
• Sequence 2: NP_476595.1
• Gene: eIF4A / 33835
• FlyBaseID: FBgn0001942
• Length: 403
• Species: Drosophila melanogaster
• Alignment Length: 379
• Identity: 127/379 - (33%)
• Similarity: 203/379 - (53%)
• Gaps: 22/379 - (5%)

  Fly    27 FEELRLYRNLLNGLKRNNFVTPTKIQAAAIPMALAKMDLIIQSKSGTGKTLIYVIAVVQSFNPNI 91
            |:::.|...||.|:....|..|:.||..||...:...|:|.|::||||||..:.||::|..:.:|
  Fly    32 FDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAILQQIDTSI 96

  Fly    92 NQPHAMIVVPTRELAIQVQDTFFHLCKSFRDFKCSAFIGGTDVAKDRKRMNES--RVIIGTPGRL 154
            .:..|:|:.||||||.|:|.....| ..:......|.||||:|.:| .|:.||  .|::|||||:
  Fly    97 RECQALILAPTRELATQIQRVVMAL-GEYMKVHSHACIGGTNVRED-ARILESGCHVVVGTPGRV 159

  Fly   155 LHLYENRVFDVSKLRLLVLDEADQLYQTKSLQHTVSKLIEAMPKNRQIIACSATYDQNLDERLAK 219
            ..:...:|.....::|.||||||::. ::..:..:..:.:.:|.:.|:|..|||...::.|....
  Fly   160 YDMINRKVLRTQYIKLFVLDEADEML-SRGFKDQIQDVFKMLPPDVQVILLSATMPPDVLEVSRC 223

  Fly   220 VMDKPMLISNSERATVLLGIRQFVYELPQQNNSVEEMRLKLQILGQIFNQLPYEQAIIFASSQMR 284
            .|..|:.|...:....|.||:||...:.|:|       .||..|..:::.|...|::||.:::.:
  Fly   224 FMRDPVSILVKKEELTLEGIKQFYVNVKQEN-------WKLGTLCDLYDTLSITQSVIFCNTRRK 281

  Fly   285 ADSYKNYLTASGIDCHLISGAMEQSERLHVFEGYRNFTMRILVATDLMARGVDSPHANLVINIDP 349
            .|.....::........:.|.|||.:|..:.:.:|:.:.|:|:.|||:|||:|....:||||.|.
  Fly   282 VDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDVQQVSLVINYDL 346

  Fly   350 PQDHVTYLHRIGRAGRFGSKGIAITFIASK-----KESQRF-----REMSKKIA 393
            |.:...|:|||||.||||.||:||.||...     |:.::|     .||...||
  Fly   347 PSNRENYIHRIGRGGRFGRKGVAINFITDDDRRILKDIEQFYHTTIEEMPANIA 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gem3	NP_524019.1	SrmB	26..409	CDD:440279	127/379 (34%)
eIF4A	NP_476595.1	DEAD-like_helicase_N	6..403	CDD:475120	127/379 (34%)