Protein Alignment Gem3 and Eif4a2

DIOPT Version :10

• Sequence 1: NP_524019.1
• Gene: Gem3 / 39195
• FlyBaseID: FBgn0011802
• Length: 1028
• Species: Drosophila melanogaster
• Sequence 2: XP_006248596.1
• Gene: Eif4a2 / 303831
• RGDID: 1309225
• Length: 408
• Species: Rattus norvegicus
• Alignment Length: 419
• Identity: 125/419 - (29%)
• Similarity: 205/419 - (48%)
• Gaps: 48/419 - (11%)

  Fly    24 VKTFEELRLYRNLLNGLKRNNFVTPTKIQAAAIPMALAKMDLIIQSKSGTGKTLIYVIAVVQSFN 88
            |..|:::.|..:||.|:....|..|:.||..||...:...|:|.|::||||||..:.|:::|...
  Rat    33 VDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLE 97

  Fly    89 PNINQPHAMIVVPTRELAIQVQDTFFHLCKSFRDFKCSAFIGGTDVAKDRKRMNES--RVIIGTP 151
            ....:..|:::.||||||.|:|.....| ..:....|.|.||||:|..:.:::...  .:::|||
  Rat    98 IEFKETQALVLAPTRELAQQIQKVILAL-GDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTP 161

  Fly   152 GRLLHLYENRVFDVSKLRLLVLDEADQLYQTKSLQHTVSKLIEAMPKNRQIIACSATYDQNLDER 216
            ||:..:...|......:::.||||||::. ::..:..:.::.:.:..:.|::..|||...::.|.
  Rat   162 GRVFDMLNRRYLSPKWIKMFVLDEADEML-SRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEV 225

  Fly   217 LAKVMDKPMLISNSERATVLLGIRQFVYELPQQNNSVEEMRLKLQILGQIFNQLPYEQAIIFASS 281
            ..|.|..|:.|...:....|.||:||..       :||....||..|..::..|...||:||.::
  Rat   226 TKKFMRDPIRILVKKEELTLEGIKQFYI-------NVEREEWKLDTLCDLYETLTITQAVIFLNT 283

  Fly   282 QMRADSYKNYLTASGIDCHLISGAMEQSERLHVFEGYRNFTMRILVATDLMARGVDSPHANLVIN 346
            :.:.|.....:.|.......:.|.|:|.||..:...:|:.:.|:|:.|||:|||:|....:||||
  Rat   284 RRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVIN 348

  Fly   347 IDPPQDHVTYLHRIGRAGRFGSKGIAITFIASKKESQRFREMSKKIATAWSVLEFPKEPMPNEFN 411
            .|.|.:...|:|||||.||||.||:||.|:.         |..|:|..
  Rat   349 YDLPTNRENYIHRIGRGGRFGRKGVAINFVT---------EEDKRILR----------------- 387

  Fly   412 FWDFEK-YNFDYYIKEENPLQEMPMPIKE 439
              |.|. ||        ..::||||.:.:
  Rat   388 --DIETFYN--------TTVEEMPMNVAD 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gem3	NP_524019.1	SrmB	26..409	CDD:440279	116/384 (30%)
Eif4a2	XP_006248596.1	DEAD-like_helicase_N	9..408	CDD:475120	125/419 (30%)