Protein Alignment Gem3 and Ddx19b

DIOPT Version :10

• Sequence 1: NP_524019.1
• Gene: Gem3 / 39195
• FlyBaseID: FBgn0011802
• Length: 1028
• Species: Drosophila melanogaster
• Sequence 2: NP_001177715.1
• Gene: Ddx19b / 234733
• MGIID: 2148251
• Length: 494
• Species: Mus musculus
• Alignment Length: 382
• Identity: 132/382 - (34%)
• Similarity: 205/382 - (53%)
• Gaps: 22/382 - (5%)

  Fly    24 VKTFEELRLYRNLLNGLKRNNFVTPTKIQAAAIPMALAK--MDLIIQSKSGTGKTLIYVIAVVQS 86
            ||:||||||...||.|:....|..|:|||..|:|:.||:  .:||.||:||||||..:|:||:..
Mouse   106 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAVLSQ 170

  Fly    87 FNPNINQPHAMIVVPTRELAIQVQDTFFHLCKSFRDFKCSAFIGGTDVAKDRKRMNESRVIIGTP 151
            ..|.......:.:.||.|||:|.......:.|.:.:.|.:..:.|..:.:.:| ::| :::||||
Mouse   171 VEPANKFAQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQK-VSE-QIVIGTP 233

  Fly   152 GRLLHLYENRVF-DVSKLRLLVLDEADQLYQTKSLQHTVSKLIEAMPKNRQIIACSATYDQNLDE 215
            |.:|.......| |..|:::.||||||.:..|:..|....::...:|:|.|::..|||::.::.:
Mouse   234 GTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWK 298

  Fly   216 RLAKVMDKPMLISNSERATVLLGIRQFVYELPQQNNSVEEMRLKLQILGQIFNQLPYEQAIIFAS 280
            ...||:..|.:|........|..|:|: |.|   .|:.||   |.|.|..::..:...||:||..
Mouse   299 FAQKVVPDPNIIKLKREEETLDTIKQY-YVL---CNNREE---KFQALCNLYGAITIAQAMIFCH 356

  Fly   281 SQMRADSYKNYLTASGIDCHLISGAMEQSERLHVFEGYRNFTMRILVATDLMARGVDSPHANLVI 345
            ::..|......|:..|....|:||.|...:|..|.|.:|....::||.|::.|||:|....::||
Mouse   357 TRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVI 421

  Fly   346 NIDPP------QDHVTYLHRIGRAGRFGSKGIAITFIASKKES---QRFRE-MSKKI 392
            |.|.|      .|:.||||||||.||||.:|:|:..:.||...   .|.:| .:|||
Mouse   422 NFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKI 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gem3	NP_524019.1	SrmB	26..409	CDD:440279	130/380 (34%)
Ddx19b	NP_001177715.1	DEAD-like_helicase_N	90..318	CDD:475120	72/213 (34%)
		SF2_C_DEAD	322..458	CDD:350174	52/142 (37%)