Protein Alignment Gem3 and Eif4a3

DIOPT Version :10

• Sequence 1: NP_524019.1
• Gene: Gem3 / 39195
• FlyBaseID: FBgn0011802
• Length: 1028
• Species: Drosophila melanogaster
• Sequence 2: NP_619610.1
• Gene: Eif4a3 / 192170
• MGIID: 1923731
• Length: 411
• Species: Mus musculus
• Alignment Length: 423
• Identity: 129/423 - (30%)
• Similarity: 209/423 - (49%)
• Gaps: 49/423 - (11%)

  Fly    18 DVAPGQVKTFEELRLYRNLLNGLKRNNFVTPTKIQAAAIPMALAKMDLIIQSKSGTGKTLIYVIA 82
            ||.|    ||:.:.|..:||.|:....|..|:.||..||...:...|:|.||:||||||..:.::
Mouse    35 DVTP----TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSVS 95

  Fly    83 VVQSFNPNINQPHAMIVVPTRELAIQVQDTFFHLCKSFRDFKCSAFIGGTDVAKDRKRMNESR-V 146
            |:|..:..:.:..|:|:.||||||:|:|.....| ..:.:.:|.|.||||:|.:|.::::..: |
Mouse    96 VLQCLDIQVRETQALILAPTRELAVQIQKGLLAL-GDYMNVQCHACIGGTNVGEDIRKLDYGQHV 159

  Fly   147 IIGTPGRLLHLYENRVFDVSKLRLLVLDEADQLYQTKSLQHTVSKLIEAMPKNRQIIACSATYDQ 211
            :.|||||:..:...|......:::|||||||::. .|..:..:..:...:|...|::..|||...
Mouse   160 VAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEML-NKGFKEQIYDVYRYLPPATQVVLISATLPH 223

  Fly   212 NLDERLAKVMDKPMLISNSERATVLLGIRQFVYELPQQNNSVEEMRLKLQILGQIFNQLPYEQAI 276
            .:.|...|.|..|:.|........|.||:||..       :||....|...|..:::.|...||:
Mouse   224 EILEMTNKFMTDPIRILVKRDELTLEGIKQFFV-------AVEREEWKFDTLCDLYDTLTITQAV 281

  Fly   277 IFASSQMRADSYKNYLTASGIDCHLISGAMEQSERLHVFEGYRNFTMRILVATDLMARGVDSPHA 341
            ||.:::.:.|.....:..:......:.|.|.|.||..:.:.:|:...|:|::||:.|||:|.|..
Mouse   282 IFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQV 346

  Fly   342 NLVINIDPPQDHVTYLHRIGRAGRFGSKGIAITFIASKKESQRFREMSKKIATAWSVLEFPKEPM 406
            :|:||.|.|.:...|:|||||:||:|.||:||.|:  |.:..|...
Mouse   347 SLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFV--KNDDIRILR------------------- 390

  Fly   407 PNEFNFWDFEKYNFDYYIKEENPLQEMPMPIKE 439
                   |.|:|       ....:.||||.:.:
Mouse   391 -------DIEQY-------YSTQIDEMPMNVAD 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gem3	NP_524019.1	SrmB	26..409	CDD:440279	119/383 (31%)
Eif4a3	NP_619610.1	DEAD-like_helicase_N	35..411	CDD:475120	129/423 (30%)
		Q motif	38..66		10/31 (32%)
		DEAD box. /evidence=ECO:0000305	187..190		2/2 (100%)