Protein Alignment Gem3 and Eif4a1

DIOPT Version :10

• Sequence 1: NP_524019.1
• Gene: Gem3 / 39195
• FlyBaseID: FBgn0011802
• Length: 1028
• Species: Drosophila melanogaster
• Sequence 2: NP_659207.1
• Gene: Eif4a1 / 13681
• MGIID: 95303
• Length: 406
• Species: Mus musculus
• Alignment Length: 409
• Identity: 127/409 - (31%)
• Similarity: 208/409 - (50%)
• Gaps: 28/409 - (6%)

  Fly    10 AGGEERSSDVAPGQ--------------VKTFEELRLYRNLLNGLKRNNFVTPTKIQAAAIPMAL 60
            |..:.||.|..|..              |.:|:::.|..:||.|:....|..|:.||..||...:
Mouse     3 ASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCI 67

  Fly    61 AKMDLIIQSKSGTGKTLIYVIAVVQSFNPNINQPHAMIVVPTRELAIQVQDTFFHLCKSFRDFKC 125
            ...|:|.|::||||||..:.|:::|....::....|:::.||||||.|:|.....| ..:....|
Mouse    68 KGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMAL-GDYMGASC 131

  Fly   126 SAFIGGTDVAKD--RKRMNESRVIIGTPGRLLHLYENRVFDVSKLRLLVLDEADQLYQTKSLQHT 188
            .|.||||:|..:  :.:|....:|:|||||:..:...|......:::.||||||::. ::..:..
Mouse   132 HACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEML-SRGFKDQ 195

  Fly   189 VSKLIEAMPKNRQIIACSATYDQNLDERLAKVMDKPMLISNSERATVLLGIRQFVYELPQQNNSV 253
            :..:.:.:..|.|::..|||...::.|...|.|..|:.|...:....|.|||||..       :|
Mouse   196 IYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYI-------NV 253

  Fly   254 EEMRLKLQILGQIFNQLPYEQAIIFASSQMRADSYKNYLTASGIDCHLISGAMEQSERLHVFEGY 318
            |....||..|..::..|...||:||.:::.:.|.....:.|.......:.|.|:|.||..:...:
Mouse   254 EREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREF 318

  Fly   319 RNFTMRILVATDLMARGVDSPHANLVINIDPPQDHVTYLHRIGRAGRFGSKGIAITFIASKKESQ 383
            |:.:.|:|:.|||:|||:|....:||||.|.|.:...|:|||||.||||.||:||..: ::::.:
Mouse   319 RSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV-TEEDKR 382

  Fly   384 RFREMSKKIATAWSVLEFP 402
            ..|::.....|  |:.|.|
Mouse   383 TLRDIETFYNT--SIEEMP 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gem3	NP_524019.1	SrmB	26..409	CDD:440279	121/379 (32%)
Eif4a1	NP_659207.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		5/17 (29%)
		DEAD-like_helicase_N	20..406	CDD:475120	122/392 (31%)
		Q motif	32..60		8/27 (30%)
		DEAD box	182..185		2/2 (100%)