DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr10 and aebp1b

DIOPT Version :9

Sequence 1:	NP_729591.1	Gene:	dpr10 / 39180	FlyBaseID:	FBgn0052057	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	XP_696022.6	Gene:	aebp1b / 567630	ZFINID:	ZDB-GENE-030131-8546	Length:	1247	Species:	Danio rerio

Alignment Length:	166	Identity:	32/166 - (19%)
Similarity:	59/166 - (35%)	Gaps:	43/166 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 TALFCCLTGLAVCYQRQSVSNNNHNNAEAKPTHAPPSHYPHGHKWNEPYFDLTMPRNITSL---- 66
            |.:..||:.|...::...::  .|:.:|.            .|...|.:.:   .||:||:
Zfish     9 TLVVLCLSLLVPSWEVNGLT--EHSKSEI------------SHTDREQHVE---DRNVTSVEDLL 56

  Fly    67 ------------VGKSAYLGCRVKHLGNKTVAWIRHRDLHILTVGTYTYTTDQRFQTSYHRDIDE 119
                        ||:...|.|:|.. ..|.:.|:...       |....|.....:...|..:..
Zfish    57 QVKIIPPYATIEVGQHKQLLCKVSS-DAKNINWVSPN-------GEKVLTKHGNLKVHNHGSVLS 113

  Fly   120 WTLQIKWAQQRDAGVYECQISTQPVRSY-SVNLNIV 154
             :|.:..|...:||:|:|..:.....|. :|.|:|:
Zfish   114 -SLTVLNANLNNAGIYKCVATNGDTESQATVKLDII 148

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr10	NP_729591.1	Ig	63..143	CDD:299845	18/95 (19%)
		IG_like	210..297	CDD:214653
		IGc2	217..287	CDD:197706
aebp1b	XP_696022.6	Ig	56..147	CDD:299845	19/99 (19%)
		IG_like	62..145	CDD:214653	18/91 (20%)
		FA58C	402..555	CDD:238014
		FA58C	403..556	CDD:214572
		Peptidase_M14_like	577..1036	CDD:299699
		Peptidase_M14NE-CP-C_like	1040..1115	CDD:200604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900