DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32053 and HXT8

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_012321.1	Gene:	HXT8 / 853216	SGDID:	S000003750	Length:	569	Species:	Saccharomyces cerevisiae

Alignment Length:	575	Identity:	112/575 - (19%)
Similarity:	203/575 - (35%)	Gaps:	147/575 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PSPDDGFHV-VPIHSDAEQHIHRNSDRQRELILQNSQTSPCCNRDLRNQPQANAVGAAALIFLTG 69
            ||.::..|: ||...:.:.....|.:...|:::.....|...           .|....|....|
Yeast    23 PSIENSSHLSVPTVEENKDFSEYNGEEAEEVVVPEKPASAYA-----------TVSIMCLCMAFG 76

  Fly    70 GVHIAWSIGFDSS----------------------LSELEVTNHVQICWFIGAIIGAL----LGG 108
            |....|..|..|.                      ||.:. |..:...:.:|:.||.|    ||.
Yeast    77 GFMSGWDTGTISGFVNQTDFLRRFGNYSHSKNTYYLSNVR-TGLIVSIFNVGSAIGCLFLSKLGD 140

  Fly   109 FFSRWFPYKTLMEFCS-----LITITGGIVMAVNRMD-LDALLAGRYMNGLANG--LAIAPTLAM 165
            .:.|          |.     ::....|||:.:..:| ......||.:.|:..|  ..:||.|
Yeast   141 IYGR----------CMGLIIVIVVYMVGIVIQIASIDKWYQYFIGRIIAGIGAGSISVLAPML-- 193

  Fly   166 AGELSVFYKRGTTTSAAEQWPTTIGIFVQIVCSHSWDVQSDFTEEQFQGVLSGVLGSIALLLAFL 230
            ..|.:..:.|||.. |..|...|..||:....::.....|           :.|...:.|.|.|.
Yeast   194 ISETAPKHIRGTLL-ACWQLMVTFAIFLGYCTNYGTKTYS-----------NSVQWRVPLGLCFA 246

  Fly   231 LSI----------ESPVDLLEQGNEQGAVQALSRLQR----PRAVTAETYDQVRDHRTYVEHHRS 281
            .:|          |||..|::.|..:.|..:.::..:    ..||.||....|..    ||...:
Yeast   247 WAIIMIGGMTFVPESPRFLVQVGKIEQAKASFAKSNKLSVDDPAVVAEIDLLVAG----VEAEEA 307

  Fly   282 MG---WRHALPALVRLSVLRALYALSLSVMVAFTLAWTSTE---VYG----------DSSGPYVL 330
            ||   |:.......::     ...|:::||:......|...   .||          ||....::
Yeast   308 MGTASWKELFSRKTKV-----FQRLTMTVMINSLQQLTGDNYFFYYGTTIFKSVGMNDSFETSIV 367

  Fly   331 FGFLRLMGSFTTSFALDSLGRKIPLLLG-LVISGCL----ACGL-----------ASRFAGSHPL 379
            .|.:.....|.:.:::|.|||:..|||| ..::.|:    :.|:           :|:.||:..:
Yeast   368 LGIVNFASCFFSLYSVDKLGRRRCLLLGAATMTACMVIYASVGVTRLYPNGKSEPSSKGAGNCTI 432

  Fly   380 TFSGNRMALWLLLIYQLFAGIAFAPSSSYLSEAFPRRIKRPCIAITYILEIIVQLLLRQMDFAAI 444
            .|:    ..::......:..:.:.    .:||.||.|::..|:::.....::...|        |
Yeast   433 VFT----CFYIFCFSCTWGPVCYV----IISETFPLRVRSKCMSVATAANLLWGFL--------I 481

  Fly   445 GSDSSYVA-----LYFFILGGLLLAGFLFSVWYMPETKDTTLLQAQFKFQEFVIP 494
            |..:.::.     .|.::..|.|...:.:..:::||||..||.:....:.:.|:|
Yeast   482 GFFTPFITSAINFYYGYVFMGCLAFSYFYVFFFVPETKGLTLEEVDEMWMDGVLP 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	86/434 (20%)
HXT8	NP_012321.1	Sugar_tr	69..530	CDD:395036	101/510 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342695
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830