DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32053 and YFL040W

DIOPT Version :9

Sequence 1:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_116613.1	Gene:	YFL040W / 850503	SGDID:	S000001854	Length:	540	Species:	Saccharomyces cerevisiae

Alignment Length:	467	Identity:	112/467 - (23%)
Similarity:	177/467 - (37%)	Gaps:	127/467 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 IGAIIGALLGGFFSRWFPYK---------TLMEFCSLITITGGIVMAVNRMDLDALLAGRYMNGL 153
            :|..|..::...|||.:.::         ||:.||.              .|:..||..|.:.|:
Yeast    80 MGCFICCIMNDRFSRIYQFQSGIIIWNIVTLLNFCI--------------WDILGLLICRMIKGM 130

  Fly   154 ANGLAIAPTLAMAGELSVFYKRGTTTSAAEQWPTTIGIFVQ---IVCSHSWDVQSDFTEEQFQGV 215
            ..|.......:.|.|:....|||:|.|.. |...||||.|.   .:....||....|......|:
Yeast   131 ILGNFSILVASYANEVIPRGKRGSTMSYI-QLCLTIGILVMHYLCIALSLWDSHFAFRIAWCIGI 194

  Fly   216 LSGVLGSIA----------LLLAFLLSIESPV--DLLEQGNE---QGAVQALSRLQRPRAVTAET 265
            :.|:|..:|          |:|...:|....:  :|.::.||   :.||..:|:::    :..:.
Yeast   195 IPGLLFWMASYALPESYHWLVLHGKMSEAQEIQHNLAKKFNESQPRDAVPEMSKIE----LAGDF 255

  Fly   266 YDQVRDHRTYVEHHRSMGWRHALPALVRLSVLRALYALSLSVMVAFT-----LAWTS--TEVYG- 322
            :..|.|          :.:...||   |.|....:..::|.::|.|:     |.:.:  .|:.|
Yeast   256 WIGVND----------LDFSKKLP---RGSFKPLILGMTLQLLVQFSGINIILGYITYICEIVGL 307

  Fly   323 -------DSSGPYVLFGFLRLMGSFTTSFALDSLGRK-IPLLLGLVISGCLACGLASRFA--GSH 377
                   .||.||    |:.::.|......:|...|| |.||.|..|||.|.. :.:.|.  |..
Yeast   308 EGNVKLFTSSIPY----FINMVLSLLPITFIDYTSRKLITLLGGFPISGLLIT-IGALFVKYGQD 367

  Fly   378 PLTFSGNRMAL-----------WLLLIYQLFAGIAFAPSSS-----YLSEAFPRRIKRPCIAI-- 424
            .....|||..:           |:|.:..|..|| ||.|.|     |.:|..|.|:|....||
Yeast   368 TKPIDGNRSLVWSIGENPFVGGWILTLCFLIVGI-FAMSLSSIPWVYTNEMLPSRVKVKGFAICV 431

  Fly   425 ------TYILEIIVQLLLRQMDFAAIGSDSSYVALYFFILGGLLLAGFLFS----VWYMPETKDT 479
                  .:||..:..:::.::.           ...|.|.|.|.   ||.|    :|: ||||..
Yeast   432 TFGWLGNFILTFLCPVMIERLK-----------GTTFIIFGSLT---FLISLSVLIWF-PETKGM 481

  Fly   480 TLLQAQFKFQEF 491
            ::.... ||.||
Yeast   482 SIEDID-KFFEF 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32053	NP_729587.1	MFS	73..428	CDD:119392	94/398 (24%)
YFL040W	NP_116613.1	MFS_HXT	28..490	CDD:340914	109/463 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900