DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10809 and tnks2

DIOPT Version :9

Sequence 1:	NP_001163403.1	Gene:	CG10809 / 39159	FlyBaseID:	FBgn0036052	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_001017008.2	Gene:	tnks2 / 549762	XenbaseID:	XB-GENE-968819	Length:	1167	Species:	Xenopus tropicalis

Alignment Length:	173	Identity:	54/173 - (31%)
Similarity:	83/173 - (47%)	Gaps:	36/173 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 SNGRK---LRTAASTCNIELLNRILEGGANPNAADEYNRSPLHLAACRGYIPIVQQLLKYGANPN 223
            |:|||   |..||....::::..:|:.||:.:|.|:.:..|||.|...|:..:.:.|:|.||:.|
Frog   208 SDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKRGASVN 272

  Fly   224 VVDSLGNTPLHLAVISASSNNFNVVVGVLLQGGASVHMYDRSNKSPLELAEAKLRLLRNRYDHPT 288
            .:|....||||    .|:|.|...|..:||..||...|.:..|||.::||             ||
Frog   273 AMDLWQFTPLH----EAASKNRVEVCSLLLSYGADPTMLNCHNKSAIDLA-------------PT 320

  Fly   289 PETAKILEDMCMLTTLILRYMVKQQRELE-----DLSALEKRL 326
            |:    |::|       |.|..|....|:     ||:.::|.|
Frog   321 PQ----LKEM-------LSYEFKGHSLLQAAREADLTRVKKHL 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10809	NP_001163403.1	Ank_2	167..263	CDD:289560	32/95 (34%)
		ANK repeat	167..193	CDD:293786	7/25 (28%)
		ANK	170..276	CDD:238125	36/105 (34%)
		ANK repeat	195..226	CDD:293786	10/30 (33%)
		ANK repeat	228..263	CDD:293786	13/34 (38%)
tnks2	NP_001017008.2	PTZ00322	28..>114	CDD:140343
		ANK repeat	61..89	CDD:293786
		PHA02876	<74..>438	CDD:165207	54/173 (31%)
		ANK repeat	91..122	CDD:293786
		ANK repeat	124..155	CDD:293786
		ANK repeat	214..242	CDD:293786	7/27 (26%)
		ANK repeat	244..275	CDD:293786	10/30 (33%)
		ANK repeat	277..308	CDD:293786	13/34 (38%)
		ANKYR	310..>472	CDD:223738	18/67 (27%)
		ANK repeat	366..398	CDD:293786
		ANK repeat	400..431	CDD:293786
		ANK repeat	434..522	CDD:293786
		PHA03095	495..>804	CDD:222980
		ANK repeat	529..557	CDD:293786
		ANK repeat	559..590	CDD:293786
		ANK repeat	592..623	CDD:293786
		ANK repeat	645..675	CDD:293786
		ANK repeat	682..710	CDD:293786
		ANK repeat	712..743	CDD:293786
		ANK repeat	745..776	CDD:293786
		SAM_tankyrase1,2	872..937	CDD:188923
		tankyrase_like	940..1161	CDD:238718
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910