DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10809 and Ankrd54

DIOPT Version :9

Sequence 1:	NP_001163403.1	Gene:	CG10809 / 39159	FlyBaseID:	FBgn0036052	Length:	358	Species:	Drosophila melanogaster
Sequence 2:	NP_001365917.1	Gene:	Ankrd54 / 223690	MGIID:	2444209	Length:	307	Species:	Mus musculus

Alignment Length:	266	Identity:	91/266 - (34%)
Similarity:	137/266 - (51%)	Gaps:	37/266 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 LPPLPLNPNASNAEYLPSL----IHP-----STLPSGSKSFKMRPRMQRLKHSYSYSNIIVQSNG 164
            ||...:....|:..||..|    :.|     ..:|:|......||. :||..:....:.:
Mouse    52 LPGRSVGRAQSSLRYLQVLWQQDVEPRDELRCKIPAGRLRRAARPH-RRLGPTGKEVHAL----- 110

  Fly   165 RKLRTAASTCNIELLNRILEGGANPNAADEYNRSPLHLAACRGYIPIVQQLLKYGANPNVVDSLG 229
            ::||.:|:..::|.:.::||.||:|.|||:..|:.||.|:|.|...|||.||.:||:||..|.||
Mouse   111 KRLRDSANANDVETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPNQQDGLG 175

  Fly   230 NTPLHLAVISASSNNFNVVVGVLLQGGASVHMYDRSNKSPLELAEAKLRLLRN---------RYD 285
            |||||||   |.:|:..|:. .||:|||.|...||:.::||.||::||.:|:.         |.:
Mouse   176 NTPLHLA---ACTNHVPVIT-TLLRGGARVDALDRAGRTPLHLAKSKLNILQEGHSQCLEAVRLE 236

  Fly   286 HPTPETAKILEDMCMLTTLILRYMVKQQRE-LEDLSALEKRLQNLSTSDDQEQVVSQTADELLAS 349
            ...|......:.:.||...:.|....:||| |:||..   |||..||.:..::|.     :||||
Mouse   237 VKQPAAPTSFQIIHMLREYLERLGRHEQRERLDDLCT---RLQMTSTKEQVDEVT-----DLLAS 293

  Fly   350 VERLSI 355
            ...||:
Mouse   294 FTSLSL 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10809	NP_001163403.1	Ank_2	167..263	CDD:289560	46/95 (48%)
		ANK repeat	167..193	CDD:293786	10/25 (40%)
		ANK	170..276	CDD:238125	50/105 (48%)
		ANK repeat	195..226	CDD:293786	15/30 (50%)
		ANK repeat	228..263	CDD:293786	18/34 (53%)
Ankrd54	NP_001365917.1	Ank_2	117..205	CDD:403870	44/91 (48%)
		ANK repeat	141..172	CDD:293786	15/30 (50%)
		ANK repeat	174..205	CDD:293786	18/34 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BJ6N
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	113	1.000	Inparanoid score	I4849
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto92334
orthoMCL	1	0.900	-	-		OOG6_108203
Panther	1	1.100	-	-	LDO	PTHR24197
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5638
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.850