Protein Alignment CG18179 and KLK14

DIOPT Version :10

• Sequence 1: NP_648340.1
• Gene: CG18179 / 39124
• FlyBaseID: FBgn0036023
• Length: 268
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 71/287 - (24%)
• Similarity: 120/287 - (41%)
• Gaps: 68/287 - (23%)

  Fly     3 LFLLTLSVALAVVAASPGFNRTSLLPQVTISEGAEGRIVNGYPAPEGKAPYIVGLLIRTDGSNSA 67
            :|||..::.:..:|             :|.|:..|.:|:.|:.......|:...||.   |....
Human     1 MFLLLTALQVLAIA-------------MTQSQEDENKIIGGHTCTRSSQPWQAALLA---GPRRR 49

  Fly    68 AVGAGTIIASDWILTAAHCLTTDYVEIHYGSN----WGWNGAFRQSVRRDNFISHPNW------- 121
            .:..|.:::..|::||||| ....:::..|.:    |   .|.:|.:|....::|||:
Human    50 FLCGGALLSGQWVITAAHC-GRPILQVALGKHNLRRW---EATQQVLRVVRQVTHPNYNSRTHDN 110

  Fly   122 ---------PAEGGRDIGLIRTPSVGFTDLINKVALPSFSEESDRFVDTWCVACGWGGMDNGNLA 177
                     ||..||.:..|        ::....|.|.          |.|...|||.: :..:|
Human   111 DLMLLQLQQPARIGRAVRPI--------EVTQACASPG----------TSCRVSGWGTI-SSPIA 156

  Fly   178 DW---LQCMDVQIISNSECEQSY-GTVASTDMCTR-RTDGKSSCGGDSGGPLVTHDNARLVGVIT 237
            .:   |||:::.|..:..|:::| .|:....:|.. ...||.||.||||||||.  ..:|.|:::
Human   157 RYPASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVC--RGQLQGLVS 219

  Fly   238 FGSVDC--HSGPSGYTRVTDYLGWIRD 262
            :|...|  ...|..||.:..|..||.:
Human   220 WGMERCALPGYPGVYTNLCKYRSWIEE 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18179	NP_648340.1	Tryp_SPc	40..263	CDD:238113	64/250 (26%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	64/250 (26%)