DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18179 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_648340.1	Gene:	CG18179 / 39124	FlyBaseID:	FBgn0036023	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001003979.1	Gene:	Tmprss11c / 408213	RGDID:	1302967	Length:	418	Species:	Rattus norvegicus

Alignment Length:	260	Identity:	82/260 - (31%)
Similarity:	128/260 - (49%)	Gaps:	44/260 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 TISEGAEGRIVNGYPAPEGKAPYIVGLLIRTDGSNSAAVGAGTIIASDWILTAAHCLTTDYVEIH 95
            ||:.|.. ::..|..|.||:.|:...|    ..:|....|| |:|::.|::|||||    :|...
  Rat   179 TITPGGH-KVAGGQDAEEGEWPWQASL----QQNNVHRCGA-TLISNSWLITAAHC----FVRSA 233

  Fly    96 YGSNWGWNGAF-------RQSVRRDNFISHPN--WPAEGGRDIGLIRTPS-VGFTDLINKVALP- 149
            ...:|..:..|       :::|:  :.:.|.|  :||. ..||.::|..| |.:.:.|.:..||
  Rat   234 NPKDWKVSFGFLLSKPQAQRAVK--SIVIHENYSYPAH-NNDIAVVRLSSPVLYENNIRRACLPE 295

  Fly   150 ---SFSEESDRFVDTWCVACGWGGM-DNGNLADWLQCMDVQIISNSECE--QSYGTVASTDM-CT 207
               .|...||      .|..|||.: .:|:..:.||...|:||.|..|.  ::||.|.:..| |.
  Rat   296 ATQKFPPNSD------VVVTGWGTLKSDGDSPNILQKGRVKIIDNKTCNSGKAYGGVITPGMLCA 354

  Fly   208 RRTDGK-SSCGGDSGGPLVTHDNAR---LVGVITFGSVDC--HSGPSGYTRVTDYLGWIRDNTGI 266
            ...:|: .:|.||||||||:.|:..   |.|::::|. :|  .:.|..|||||.|..||...||:
  Rat   355 GFLEGRVDACQGDSGGPLVSEDSKGIWFLAGIVSWGD-ECALPNKPGVYTRVTHYRDWISSKTGL 418

Fly 267 266
Rat 419 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18179	NP_648340.1	Tryp_SPc	39..260	CDD:214473	75/244 (31%)
CG18179	NP_648340.1	Tryp_SPc	40..263	CDD:238113	77/246 (31%)
Tmprss11c	NP_001003979.1	SEA	62..157	CDD:279699
		Tryp_SPc	186..412	CDD:214473	75/244 (31%)
		Tryp_SPc	187..415	CDD:238113	77/246 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910