DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18179 and tmprss2.12

DIOPT Version :9

Sequence 1:	NP_648340.1	Gene:	CG18179 / 39124	FlyBaseID:	FBgn0036023	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	XP_031752400.1	Gene:	tmprss2.12 / 100497514	XenbaseID:	XB-GENE-22065925	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	256	Identity:	79/256 - (30%)
Similarity:	120/256 - (46%)	Gaps:	46/256 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ISEGAEGRIVNGYPAPEGKAPYIVGLLIRTDGSNSAAVGAGTIIASDWILTAAHCLTTDYVEIHY 96
            :|...|.|||.|..|..|..|:.|.|  :.|.:|   :..|::||::||:|||||:..|   ...
Frog   253 LSTYGESRIVGGSSASIGDWPWQVNL--QYDDTN---LCGGSVIAANWIVTAAHCVQGD---TSS 309

  Fly    97 GSNWGWNGAFRQSVRR-----------DNFISHPNWPAE-GGRDIGLIR-TPSVGFTDLINKVAL 148
            .|.|   .||...::.           |..|.||::.:: ...||.|:: ..|:.|:.:...|.|
Frog   310 PSLW---KAFIGKIKMPSYYDSSAYSVDRIIVHPDYSSQTNSNDIALMKLKTSIAFSSISRPVCL 371

  Fly   149 PSFSEESDRFVDTW-----CVACGWG-GMDNGNLADWLQCMDVQIISNSECEQSY---GTVASTD 204
            |::..:       |     |...||| ....|:::..|:...|.:||.:.|.|:.   |.:.|:.
Frog   372 PNYGMQ-------WEEGQPCYISGWGTTSQKGSISSVLKYAMVPLISPTTCNQTIMYNGAITSSM 429

  Fly   205 MCT-RRTDGKSSCGGDSGGPLVTHDNAR--LVGVITFGSVDCHS--GPSGYTRVTDYLGWI 260
            :|. ....|..||.|||||||||..|:.  |||..::|. .|.:  .|..|..:|.:|.||
Frog   430 ICAGYPKGGVDSCQGDSGGPLVTKTNSLWWLVGDTSWGD-GCANVYRPGVYGNMTVFLQWI 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18179	NP_648340.1	Tryp_SPc	39..260	CDD:214473	75/247 (30%)
CG18179	NP_648340.1	Tryp_SPc	40..263	CDD:238113	76/248 (31%)
tmprss2.12	XP_031752400.1	LDLa	127..155	CDD:238060
		SRCR_2	160..255	CDD:406055	0/1 (0%)
		Tryp_SPc	261..489	CDD:238113	74/246 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910