Protein Alignment path and SLC36A1

DIOPT Version :10

• Sequence 1: NP_648327.1
• Gene: path / 39106
• FlyBaseID: FBgn0036007
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: XP_047272876.1
• Gene: SLC36A1 / 206358
• HGNCID: 18761
• Length: 507
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 154/499 - (30%)
• Similarity: 247/499 - (49%)
• Gaps: 53/499 - (10%)

  Fly     7 SGSKHAPQEMEQFLPGEGKVMYKIQPRKSDTEQALAGNDFDPFALRD------------------ 53
            :.:..|...||...|..|.:.....|..:.:.|.|...|:..::..|
Human     3 ASTPEATPNMELKAPAAGGLNAGPVPPAAMSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPG 67

  Fly    54 ------NPHPTTDNETLTHLLKASLGTGILGMPFAFMCSGLIMGIFSTIFTAFICTHCSYVLVKC 112
                  ..:.||..:||.||||.::|||:||:|.|...:|::||..|.:....:..||..:||||
Human    68 SYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKC 132

  Fly   113 GHKLYYRTRRTKMTFAEIAEAAFQKGP-KWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVASNF 176
            .|....|..::.:.:.:......:..| .|.|..|...:..:.|.|.:|..|.|.||.|.:|.||
Human   133 AHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNF 197

  Fly   177 EQLISYWTGTAVSLRMLICIMLVP--------------LILIAWVPNLKYLAPVSMVANVFMGLG 227
            :|:|....||..:......::|.|              |:|:.::.||:.|:..|::||:.|.:.
Human   198 KQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVS 262

  Fly   228 LGITFYYLVQDLPPVEERESVV-WSTLPQFFSITIFAMEAIGVVMPLENNMKTPQSFLGICGVLS 291
            |.:.:.::||.:|.......|. |.|.|.||...||:.|.||:|:||||.||.|:.|..|   |.
Human   263 LVMIYQFIVQRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLI---LY 324

  Fly   292 QGMSGVTLIYMLLGFLGYLRYGSATGESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEI 356
            .||..||::|:.||.||||::|:....||||||| ..|..|:||:|.|:.::.|:.|||:|..||
Human   325 LGMVIVTILYISLGCLGYLQFGANIQGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVPAEI 388

  Fly   357 I----WDGIKEKCKKRPTLVNYVLRTVLVTAAVVLAVAVPTIGPFMGLIGAFCFSILGLIFPVVI 417
            |    .....|.|:   .:|:..:|||||....:||:.:|.:...:.|:|:...|.|.||.|.::
Human   389 IIPFFVSRAPEHCE---LVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLL 450

  Fly   418 ELIVHWESGFGKYNWILWKNAIITLCGIGALVFGTQAAIKDIVK 461
            |:...:..|.....  ::|:|:|::.|....|.||..|:.::::
Human   451 EVTTFYSEGMSPLT--IFKDALISILGFVGFVVGTYEALYELIQ 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
path	NP_648327.1	SLC5-6-like_sbd	56..456	CDD:444915	143/419 (34%)
SLC36A1	XP_047272876.1	SLC5-6-like_sbd	78..484	CDD:444915	142/414 (34%)