Protein Alignment CG3529 and Hgs

DIOPT Version :10

• Sequence 1: NP_648315.1
• Gene: CG3529 / 39093
• FlyBaseID: FBgn0035995
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_038942636.1
• Gene: Hgs / 56084
• RGDID: 69225
• Length: 860
• Species: Rattus norvegicus
• Alignment Length: 526
• Identity: 113/526 - (21%)
• Similarity: 188/526 - (35%)
• Gaps: 178/526 - (33%)

  Fly    22 IEAATDANLASENWAANMEICDMINESSDTARDAMRAIRKRLSQNAGKNNQVVMYTLTVLETCVK 86
            ::.||...|...:|.:.::|||:|.:....|:.|:.:|:|:::.   ||..|.:|.|.|:|:.||
  Rat    74 LDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVND---KNPHVALYALEVMESVVK 135

  Fly    87 NCGKAFHVLVAQKDFINELVKLIGPKNDPPAAMQEKVLSLIQIWADAFKNQPDLNGVTQMYMELK 151
            |||:..|..||.|..:.||.:|:  |......::.|:|.|||.||.||:|:|....|...|..:|
  Rat   136 NCGQTVHDEVANKQTMEELKELL--KRQVEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMK 198

  Fly   152 NKGIEFPA-NDLDAMAPIYTPQRSVPEMPPQLVAAQQ-H-------TISPQHMAAAAAA--AAAA 205
            .:|..||. .:.|||   :..:|:     |..|.|:: |       .::.:|...|...  ....
  Rat   199 VEGHVFPEFKESDAM---FAAERA-----PDWVDAEECHRCRVQFGVVTRKHHCRACGQIFCGKC 255

  Fly   206 AAPPSTGPLHLTPEQAAKLRSELEIVSNNMSILSEMLSVLKPGQESPDDYALLNELTSTCKEMQS 270
            ::..||.|         |...|.|:            .|.:|                 |.|
  Rat   256 SSKYSTIP---------KFGIEKEV------------RVCEP-----------------CYE--- 279

  Fly   271 RIVDLIGRVQDDELTAEFLRINDELNNVFLRHQRYEKNRSQGQGAGVTSPSAVLGAAMGLPGVGA 335
                                   :||           .:::|:.|..|.
  Rat   280 -----------------------QLN-----------KKAEGKAASTTE---------------- 294

  Fly   336 AGAGATTVATLPPPPTTTAVSN----TPQSDQLLIDLIESSEEAQLPQSLGQISLGGGAPIGVQR 396
                      |||...|:.:|.    .|:.|:   ..::..||.||..:|.|
  Rat   295 ----------LPPEYLTSPLSQQSQLPPKRDE---TALQEEEELQLALALSQ------------- 333

  Fly   397 SARPADEFDMLAQSRTDGNHKSDLLRDIPSVDAAAGSVTATASPYKPNQPQQAQRSAGEPPVVSK 461
              ..|:|.:.:.|..|...|.......:.|....|||:.::                   ||.|.
  Rat   334 --SEAEEKERMRQKSTYTAHPKSEPAPLASSAPPAGSLYSS-------------------PVNSS 377

  Fly   462 STKENEID-EMEAWLGSSHIEGIEELTSSEFDKFLEERAAAAENLPTISASNSAASATTGSAGAD 525
            :....:|| |:..:|..::.|..:|          |.|.:...:.| :..:..||....|....:
  Rat   378 APLAEDIDPELARYLNRNYWEKKQE----------EARKSPTPSAP-VPLTEPAAQPGEGHTAPN 431

  Fly   526 SLRKTP 531
            |:.:.|
  Rat   432 SMVEAP 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3529	NP_648315.1	VHS_Tom1_like	17..154	CDD:340768	46/131 (35%)
		GAT_TOM1_like	222..307	CDD:410581	9/84 (11%)
Hgs	XP_038942636.1	VHS_Hrs	68..205	CDD:340771	47/135 (35%)
		FYVE_Hrs	221..281	CDD:277260	15/123 (12%)
		PLN03209	<283..441	CDD:178748	42/229 (18%)
		GAT_Hrs	467..562	CDD:410592
		Smc	<515..>620	CDD:440809
		G_path_suppress	560..809	CDD:464961