Protein Alignment CG3529 and hgs

DIOPT Version :10

• Sequence 1: NP_648315.1
• Gene: CG3529 / 39093
• FlyBaseID: FBgn0035995
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: XP_005164430.1
• Gene: hgs / 334175
• ZFINID: ZDB-GENE-030131-6107
• Length: 773
• Species: Danio rerio
• Alignment Length: 567
• Identity: 133/567 - (23%)
• Similarity: 206/567 - (36%)
• Gaps: 153/567 - (26%)

  Fly     7 VGALGNVFSTPVGQRIEAATDANLASENWAANMEICDMINESSDTARDAMRAIRKRLSQNAGKNN 71
            :|..|..|.    :.:|.||...|...:|.:.::|||:|.:....|:.|:.||:|:|:.   ||.
Zfish     1 MGKGGGTFE----RLLEKATSQLLLETDWESILQICDLIRQGDTQAKYAIGAIKKKLND---KNP 58

  Fly    72 QVVMYTLTVLETCVKNCGKAFHVLVAQKDFINELVKLIGPKNDPPAAMQEKVLSLIQIWADAFKN 136
            .|.:|.|.|||:.|||||:..|..||.|..:.||.:|.  |..|...::.|:|.|||.||.||:|
Zfish    59 HVALYALEVLESVVKNCGQTIHDEVASKQTMEELKELF--KKQPEPNVKNKILYLIQAWAHAFRN 121

  Fly   137 QPDLNGVTQMYMELKNKGIEFPA-NDLDAM-----APIYTPQRSVPEMPPQL-VAAQQH------ 188
            :|....|...|..:|.:|..||. .:.|||     ||.:...........|. |..::|
Zfish   122 EPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVMTRKHHCRACG 186

  Fly   189 ------------------------------TISPQHMAAAAAAAAAAAAPPSTGPLHLTPEQAAK 223
                                          .|...|.:.:.....|....|||||..|.||...
Zfish   187 QIFCGKCSSKYSTIPKFGIEKEVRVCEPCFEILNNHPSLSPPPRKAEGKAPSTGPSELPPEYLT- 250

  Fly   224 LRSELEIVSNNMSILSEMLSVLKPGQESP---DDYALLNELTSTCKEMQSRIVDLIGRVQDDELT 285
                        |.||:...|: |.:..|   |:.||..|     :|:|..|
Zfish   251 ------------SPLSQQSQVV-PTESMPPKRDEAALQEE-----EELQLAI------------- 284

  Fly   286 AEFLRINDELNNVFLRHQRYEKNRSQGQGAGVTSPSAVLGAAMGLPGVGAAGAGATTVATLPPPP 350
                        ...:.:..||.|.:.:     :|.:....|...|    ..:.|..|:||...|
Zfish   285 ------------ALSQSEAEEKERMRQK-----NPYSAYPKADPTP----VTSSAPPVSTLYSSP 328

  Fly   351 TTTAVSNTPQSDQLLIDLI---------ESSEEAQLPQSLGQISLGGGAPIGVQ-RSARPADEFD 405
            ..::..:..:.|..|...:         |...::..|.:...:||....|:... .|..|....:
Zfish   329 VNSSAPSAEEVDPELARYLNRTYWEKKQEEVRKSPTPSAPAPVSLAEPVPVSQPVESHVPVQPIN 393

  Fly   406 MLAQSRTDG----NHKSDLLRDIPSVDAAAGSVTATASPYKPNQPQQAQRSAGEPPVVS--KSTK 464
            ::.|...:|    ||:..|       .|...|||...:..|.|. .:.:....:..|:|  :|..
Zfish   394 IVEQQYQNGESEENHEQFL-------KALQNSVTTFLNRMKSNH-MRGRSITNDSAVLSLFQSIN 450

  Fly   465 E---------NEIDEMEAWLGSSHIEGIEELTSSEFDKFLEERAAAA 502
            .         |::||...     :.||::       ||..:.|.|.|
Zfish   451 NMHPQLLEILNQLDEKRL-----YYEGLQ-------DKLAQVRDARA 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3529	NP_648315.1	VHS_Tom1_like	17..154	CDD:340768	51/136 (38%)
		GAT_TOM1_like	222..307	CDD:410581	13/87 (15%)
hgs	XP_005164430.1	VHS_Hrs	6..143	CDD:340771	53/145 (37%)
		FYVE_Hrs	159..219	CDD:277260	3/59 (5%)
		PHA03247	<223..391	CDD:223021	42/220 (19%)
		DUF3432	302..>335	CDD:403204	8/36 (22%)
		GAT_Hrs	409..504	CDD:410592	20/97 (21%)
		Smc	<457..>554	CDD:440809	10/41 (24%)
		CwlO1	<480..730	CDD:443091	3/6 (50%)