Protein Alignment CG3529 and Tom1l2

DIOPT Version :10

• Sequence 1: NP_648315.1
• Gene: CG3529 / 39093
• FlyBaseID: FBgn0035995
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001390817.1
• Gene: Tom1l2 / 216810
• MGIID: 2443306
• Length: 528
• Species: Mus musculus
• Alignment Length: 566
• Identity: 240/566 - (42%)
• Similarity: 320/566 - (56%)
• Gaps: 79/566 - (13%)

  Fly    10 LGNVFSTPVGQRIEAATDANLASENWAANMEICDMINESSDTARDAMRAIRKRLSQNAGKNNQVV 74
            |||.|||||||.:|.|||.:|.||:|..||||||:|||:.:..:||:||::||||.|  :|.:.|
Mouse     5 LGNPFSTPVGQCLEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLSGN--RNYREV 67

  Fly    75 MYTLTVLETCVKNCGKAFHVLVAQKDFINE-LVKLIGPKNDPPAAMQEKVLSLIQIWADAFKNQP 138
            |..||||||||||||..||:|||.:|||:. |||:|.|||:||..:|:|||:|||.|||||::.|
Mouse    68 MLALTVLETCVKNCGHRFHLLVANRDFIDSVLVKIISPKNNPPTIVQDKVLALIQAWADAFRSSP 132

  Fly   139 DLNGVTQMYMELKNKGIEFPANDLDAMAPIYTPQRSVPEMPPQLVAAQQHTISPQHMAA------ 197
            ||.||..:|.|||.:|||||..||||::||:|||||||||.|.....:..| .|:..|.
Mouse   133 DLTGVVHIYEELKRRGIEFPMADLDALSPIHTPQRSVPEMDPAATIPRSQT-QPRTTAGTYSSPP 196

  Fly   198 -AAAAAAAAAAPPSTGPLHLTPEQAAKLRSELEIVSNNMSILSEMLSVLKPGQESPDDYALLNEL 261
             |:.:...|.|...|||:....||.|:|||||:||..|..::||||:.:.||||...|..||.||
Mouse   197 PASYSTLQAPALSVTGPITANSEQIARLRSELDIVRGNTKVMSEMLTEMVPGQEDSSDLELLQEL 261

  Fly   262 TSTCKEMQSRIVDLIGRVQDDELTAEFLRINDELNNVFLRHQRYEKNRS----QGQGAGVTS--- 319
            ..||:.||.|||:||.||.::|:|.|.|.:||:|||||||::|:|:.||    |....||.|
Mouse   262 NRTCRAMQHRIVELISRVSNEEVTEELLHVNDDLNNVFLRYERFERYRSGRSVQNASNGVLSEVT 326

  Fly   320 PSAVLGAAMGLPGVGAAGAGATTVATLPPPPTTTAVSNTPQSDQLLIDLIESSEEAQLPQSLGQI 384
            ...::....|.|.|.:...|:|.      ||::.                 ||:.|.|  .||..
Mouse   327 EDNLIDLGPGSPAVVSPMVGSTA------PPSSL-----------------SSQLAGL--DLGTE 366

  Fly   385 SLGGGAPIGVQRSARPADEFDMLAQSRTDGNHKSDLLRDIPSVD-AAAGSVTATASPYKPNQPQQ 448
            |:.|  .:...:..:|.|.|||.||:|  ||..::..:.:...| .|.|.:.:.....|.|...:
Mouse   367 SVSG--TLSSLQQCKPQDGFDMFAQTR--GNSLAEQRKTVTYEDPQAVGGLASALDNRKQNSEMR 427

  Fly   449 AQ-------------RSAGEPPVVSKSTKENEIDEMEAWL-----GSSHIEGIEELTSSEFDKFL 495
            .:             .:.|..||...|.    :|::|.||     |....||:   ||.||||||
Mouse   428 GRGGDSDLQPIDSWLMTQGMIPVAQPSV----MDDIEVWLRTDLKGDDLEEGV---TSEEFDKFL 485

  Fly   496 EERAAAAENLPTISASNSAASATTGSAGADSLRKTPKKPGAEEDLL 541
            ||||.|||.:|.:.:..:.|.|...:.      .|.|||...:|.|
Mouse   486 EERAKAAETVPDLPSPPTEAPAPASNT------STRKKPERSDDAL 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3529	NP_648315.1	VHS_Tom1_like	17..154	CDD:340768	83/137 (61%)
		GAT_TOM1_like	222..307	CDD:410581	47/84 (56%)
Tom1l2	NP_001390817.1	VHS_Tom1L2	12..148	CDD:340793	83/137 (61%)
		GAT_TM1L2	218..309	CDD:410585	50/90 (56%)