Protein Alignment Rdl and Gabrp

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_112291.1
• Gene: Gabrp / 81658
• RGDID: 620532
• Length: 440
• Species: Rattus norvegicus
• Alignment Length: 542
• Identity: 148/542 - (27%)
• Similarity: 249/542 - (45%)
• Gaps: 156/542 - (28%)

  Fly    64 DSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVE 128
            ::.:..|:|.:|||:||.||.:.:|:.:.||||:||..||:|...|.||.||||||.:.   |.:
  Rat    42 ENLTAGYNKFLRPNFGGDPVRIALTLDIASISSISESNMDYTATIYLRQRWTDPRLVFE---GNK 103

  Fly   129 TLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFP 193
            :.::.:..::.:|||||:.|..|:|:.|..|..|..||:..:|::..::|:|.|.:|.|:|..:|
  Rat   104 SFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVTCNMDLSKYP 168

  Fly   194 MDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTGNYSRLA 258
            ||.|.|.:::||:||...|:.:.|..|..||.....:.|.|:.:..:....|.....||||:||.
  Rat   169 MDTQTCKLQLESWGYDGNDVEFSWLRGNDSVRGLENLRLAQYTIQQYFTLVTVSQQETGNYTRLV 233

  Fly   259 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPK 323
            .:.:..|::.|::::.|:||..:|::||||||::..:.|||..:||||||:|||||..:..:||.
  Rat   234 LQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLESVPARTCIGVTTVLSMTTLMIGSRTSLPN 298

  Fly   324 IS-YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGANQQQA 387
            .: ::|:||||||.||..||.:|||||...|            .::|::|.:.:
  Rat   299 TNCFIKAIDVYLGICFSFVFGALLEYAVAHY------------SSLQQMAVKDR----------- 340

  Fly   388 NPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSN-- 450
                               ||......||:                       .:....::|:
  Rat   341 -------------------GPAKDSEEVNI-----------------------TNIINSSISSFK 363

  Fly   451 RPIGFSNIQ---QNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPG 512
            |.|.|::|:   .||.          :.::..|..|
  Rat   364 RKISFASIEISGDNVN----------YSDLTMKASD----------------------------- 389

  Fly   513 QGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKV--KDINKLLGI----TPSDIDKY 571
                                                 |.|.|  :.|.:::..    .||::|:|
  Rat   390 -------------------------------------KFKFVFREKIGRIIDYFTIQNPSNVDRY 417

  Fly   572 SRIVFPVCFVCFNLMYWIIYLH 593
            |:::||:.|:..|:.||..|::
  Rat   418 SKLLFPLIFMLANVFYWAYYMY 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	64/182 (35%)
		Cys-loop	185..199	CDD:349809	7/13 (54%)
		Neur_chan_memb	274..588	CDD:460753	71/325 (22%)
Gabrp	NP_112291.1	LIC	43..437	CDD:455710	147/537 (27%)
		LGIC_ECD	60..241	CDD:475126	65/183 (36%)