Protein Alignment Rdl and gabrg1

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_009305483.1
• Gene: gabrg1 / 556202
• ZFINID: ZDB-GENE-141215-66
• Length: 454
• Species: Danio rerio
• Alignment Length: 537
• Identity: 151/537 - (28%)
• Similarity: 228/537 - (42%)
• Gaps: 136/537 - (25%)

  Fly    58 NISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYR 122
            :::.||:.....||.::||:.|..|..:...:||.||..:..:.|::|:|.:|.|.|.|.||.:.
Zfish    54 DVTLILNKLLQGYDNKLRPDIGVRPTVIETAVYVNSIGPVDPINMEYTIDIFFAQTWYDSRLKFN 118

  Fly   123 KRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPM 187
            .  .::.|.:.|..:..||:|||||.|.::|..|..||.|..:|:..:|.:..::||||.|.|.:
Zfish   119 S--SMKLLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRLWSNGRVMYTLRLTINAECYL 181

  Fly   188 NLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTG 252
            .|..||||...|.:|..|:||...:|:|.|:.....|.......|.||..:|.|..:...|..:|
Zfish   182 KLHNFPMDEHSCPLEFSSYGYPKNEIQYRWQRRSVEVADQRYWRLYQFAFVGLRNSSDVANTQSG 246

  Fly   253 NYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSST 317
            .|..:.......|.|||:.||.|||..:||::||||||:|::|.|||.:||:|||||||||.:.:
Zfish   247 EYVVMTIFFDLSRRMGYFTIQTYIPCSMIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIS 311

  Fly   318 NAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQQLDGA 382
            ..:|||:|||.::|:::..||:..||:|:||.|:.|.....|.:|.:....||
Zfish   312 RKSLPKVSYVTAMDLFVSVCFIFTFAALMEYGTLHYFTSNRQNKKTKSSHAQK------------ 364

  Fly   383 NQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQT 447
                           |..|.:.|        |.::.....:.|.|......:....|
Zfish   365 ---------------PSMVNIRP--------GTSLLQMNNIAPYHEDDDYAYECLDG-------- 398

  Fly   448 VSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPG 512
                             :.|:.....|.:.|          .|...||.::
Zfish   399 -----------------KDCTSFFCCFDDCR----------SGAWRENRMH-------------- 422

  Fly   513 QGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSDIDKYSRIVFP 577
                                          .|:                    |.||.||||.||
Zfish   423 ------------------------------VHV--------------------SKIDSYSRIFFP 437

  Fly   578 VCFVCFNLMYWIIYLHV 594
            ..|..|||:|||.||::
Zfish   438 TAFGLFNLVYWIGYLYL 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	58/182 (32%)
		Cys-loop	185..199	CDD:349809	6/13 (46%)
		Neur_chan_memb	274..588	CDD:460753	74/313 (24%)
gabrg1	XP_009305483.1	LIC	58..451	CDD:455710	149/528 (28%)
		LGIC_ECD_GABAAR_G	79..260	CDD:349801	58/182 (32%)
		Cys-loop	179..193	CDD:349801	6/13 (46%)