Protein Alignment Rdl and SecCl

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_648984.2
• Gene: SecCl / 39949
• FlyBaseID: FBgn0036727
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 610
• Identity: 143/610 - (23%)
• Similarity: 236/610 - (38%)
• Gaps: 155/610 - (25%)

  Fly    20 LLTIWLAINMALIAQETGHKRIHTVQAATGGGSMLGDVNISAILDSFSVSYDKRVRP-NYGGP-- 81
            :|:||.::.:....:|        ..:....||:.....|..:  :....||:..|| .|...
  Fly    17 VLSIWTSVGVKAEEEE--------CPSMADAGSLQQTQLIQRL--THVCRYDRLERPFEYDSDGK 71

  Fly    82 --PVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPD 144
              |:.|...:||..:.:|:...:.|.:....:..:.|.||||:.....:.:.......:.:|:|.
  Fly    72 RLPIVVKTRIYVYFLQNLNSDLLQFKMHALLQLRFQDKRLAYKAFNRSDNILGQKHLSERLWLPH 136

  Fly   145 TFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYT 209
            .||.||::|........:....:...|::..|.|:..:..|.||.|.||.|:|.|...:||:.|.
  Fly   137 IFFANERESSILGTDEKDVLTSLSPEGNVIISTRMQASLYCWMNFQKFPFDQQFCSTVLESWMYN 201

  Fly   210 MRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEI-----NLT----TGNYSRLACEIQFVR 265
            ..|:...| :..:.:....|:.|.::.:.......|.:     ||.    .||||.|:..:...|
  Fly   202 TSDLILEW-EPHTPISFDPEMRLTEYNMAQFWHNTTIVQSDGDNLRHGAFAGNYSSLSFTVNLKR 265

  Fly   266 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSI 330
            .:|:||:..|:||.:||.||||||||..:|:|.|:.||.:|:|:..||.||.:..|||:||:|..
  Fly   266 EIGFYLLDYYLPSMMIVAISWVSFWLQADASPPRIMLGTSTMLSFITLSSSQSKNLPKVSYIKVS 330

  Fly   331 DVYLGTCFVMVFASLLEYATVGYMAKR---IQMRKQRFMAIQK---IAEQKKQQLDG--ANQQQA 387
            :|:...|...:|.||:|:|.|..:.:|   |:::|.....|.|   .....::|:.|  :|:.:|
  Fly   331 EVWFLGCTFFIFGSLVEFAFVNTIWRRKENIELKKVNSKYIIKSTLTPRPARRQIGGSLSNESRA 395

  Fly   388 NPNPNAN--VGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHSHGHPHAP------ 444
            ....:.:  |.....|..|       .|.||              .|.:.:...||:.|
  Fly   396 RSCSSLDNIVSSTESVRNG-------NGTVN--------------QGFNNYLTVHPNLPIIRTEC 439

  Fly   445 --KQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSH 507
              ..|||.                ||                         ..|.|.
  Fly   440 AEADTVSI----------------CS-------------------------ARTNND-------- 455

  Fly   508 GPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITPSD----I 568
                                                |::...|.|| ........:||.:    |
  Fly   456 ------------------------------------HIVDVDKDKK-DTPPTFTTMTPQEIAMWI 483

  Fly   569 DKYSRIVFPVCFVCFNLMYW-IIYL 592
            |:.||.:||..|:.||.:|| .:|:
  Fly   484 DRRSRFLFPAMFLAFNALYWTFVYV 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	44/191 (23%)
		Cys-loop	185..199	CDD:349809	8/13 (62%)
		Neur_chan_memb	274..588	CDD:460753	79/335 (24%)
SecCl	NP_648984.2	LIC	43..505	CDD:455710	136/571 (24%)