Protein Alignment Rdl and gabra6a

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_005173169.1
• Gene: gabra6a / 393704
• ZFINID: ZDB-GENE-040426-1692
• Length: 435
• Species: Danio rerio
• Alignment Length: 547
• Identity: 163/547 - (29%)
• Similarity: 238/547 - (43%)
• Gaps: 145/547 - (26%)

  Fly    50 GGSMLGDVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFW 114
            |...:...||:.|||.....||.|:||..|....||...::|.|...:|:|.|:||:|.:|||.|
Zfish    18 GKQKINSENITRILDGLLEGYDNRLRPGSGVSVTEVKTDIFVTSFGPVSDVNMEFTMDMFFRQMW 82

  Fly   115 TDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRL 179
            .|.|||:  :..:|.|.:.:..:..||.|||||.|.::|..|..|:.|:..|:..:|::..::||
Zfish    83 VDERLAF--QGPIEILPLNNRMVDKIWTPDTFFRNARKSLAHNMTSPNKLFRIMQNGTVFYTMRL 145

  Fly   180 TITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGL-SSVGMSSE-VELPQFRVLGHRQ 242
            |::|.|||.|:.||||...|.:...|:.||.|:|.|.||.|| :||....| ..|.|:.:||...
Zfish   146 TVSAVCPMVLRDFPMDGHTCPLYFGSYAYTNREIVYTWRKGLEASVDFPPESSSLLQYDLLGQTL 210

  Fly   243 RATEINLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTV 307
            .......:||.||.........|.:||:|||.|||..::|::|.||||:|:.:.|||...|:|||
Zfish   211 FTETYKFSTGLYSVQVVHFYLQRKLGYHLIQTYIPLIMVVVLSQVSFWINKESVPARTVAGITTV 275

  Fly   308 LTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIA 372
            ||||||..|..::|||:||..::|.::..||..|.::|:|:|.|.|.|.....|:...:....|.
Zfish   276 LTMTTLSISARSSLPKVSYATAMDWFIAVCFAFVASALVEFAAVNYYATLEANRENHKLPRGSIV 340

  Fly   373 EQKKQQLDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHAHS 437
            |.:.|   |::.:..:|..:.:                                     .:....
Zfish   341 ESQAQ---GSDDEPESPQSDTS-------------------------------------AYSRKR 365

  Fly   438 HGHP--HAPKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGG 500
            .|:|  .||:..|                       |:|.:
Zfish   366 RGYPVSEAPRTRV-----------------------PIFLQ------------------------ 383

  Fly   501 RGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITP 565
                                     |...||                          |.:|..|
Zfish   384 -------------------------GSAFPP--------------------------NMMLAGT- 396

  Fly   566 SDIDKYSRIVFPVCFVCFNLMYWIIYL 592
            |.|||||||:||:.|..|||:||.|||
Zfish   397 SAIDKYSRILFPLAFGIFNLVYWYIYL 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	68/184 (37%)
		Cys-loop	185..199	CDD:349809	8/13 (62%)
		Neur_chan_memb	274..588	CDD:460753	72/315 (23%)
gabra6a	XP_005173169.1	LIC	2..422	CDD:455710	160/544 (29%)
		LGIC_ECD	37..234	CDD:475126	74/198 (37%)