Protein Alignment Rdl and CG8916

DIOPT Version :10

• Sequence 1: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 604
• Identity: 174/604 - (28%)
• Similarity: 273/604 - (45%)
• Gaps: 122/604 - (20%)

  Fly    26 AINMALIAQETGHKRIHTVQAATGGGSMLGDVNISAILDSFSVSYDKRVRPNYG-GPPVEVGVTM 89
            |.|::..:.|..::|....:||   ..||.. |||.||::....|::...|.:| |.|..|...:
  Fly    79 ATNLSYSSSEISNQRRVRRKAA---ADMLSR-NISMILENLLKRYEQSQLPTHGQGVPTVVQTNI 139

  Fly    90 YVLSISSLSEVKMDFTLDFYFRQFWTDPRLAYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSY 154
            .:.|:..:||:.||:::|.||||:|.|.||:: |.| :::||:..:.:..||.|||:|.|.|.|.
  Fly   140 LIRSMGPVSELDMDYSMDCYFRQYWRDKRLSF-KGP-IKSLSLSIKMLDKIWRPDTYFYNGKHSQ 202

  Fly   155 FHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWRD 219
            .|:.|..|:.:|:..:|.|..|:||||.|:|||.||.||||||.|.:.|.|:||..:.:.|.|::
  Fly   203 IHMITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKN 267

  Fly   220 GLSSVGMSSEVELPQFRVLGHRQRATEINLTT----GNYSRLACEIQFVRSMGYYLIQIYIPSGL 280
            ...:|.....:.|.||.::....|    |.||    |::|.|.......|..||:|||:|:|..|
  Fly   268 QDDAVSFVPGMTLNQFDLISMMHR----NFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCIL 328

  Fly   281 IVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASL 345
            ||::||||||::|.||..||:|.||:|||::|:...:...|||:.|..::|.:|...|:...|:|
  Fly   329 IVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATL 393

  Fly   346 LEYATVGYMAK-----RIQMRKQ-RFMAIQKIAEQKKQQLDGANQQQANP-----NPNANVGGPG 399
            ||:|.|.|..|     ..|:..| ..:.|.........::||..:..|:|     :.|.:.....
  Fly   394 LEFAGVHYFTKLGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDN 458

  Fly   400 GVGVGPGGPGGPGGGV-NVGVGMGMGPEHGHGHGHHAHSHGHPHAPKQTVSNRPIGFSNIQQNVG 463
            ..|.........|..| |....:|:..|                   .::.|...|...:::|
  Fly   459 EAGASESVESKSGVCVCNKNDALGLEYE-------------------VSLQNSLAGAGFLKRN-- 502

  Fly   464 TRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGPGQGGGPPGGGGGGGGGG 528
                :|..|.:       :|| ::....|:|.|..
  Fly   503 ----AIFCPTY-------NDP-SYILPNTMERTTQ------------------------------ 525

  Fly   529 GPPEGGGDPEAAVPAH-----LLHPGKVKKVKD----------------INKLLGITPSDIDKYS 572
                  .:|.|....|     |......:|.::                :|.:     |.||:.:
  Fly   526 ------TEPPAVSRLHQMWMCLKSDNSFRKQRERNAAAQKSEQGGANCYVNSV-----SLIDRVA 579

  Fly   573 RIVFPVCFVCFNLMYWIIY 591
            ||.||:.|...||:||..|
  Fly   580 RIAFPMSFAFLNLLYWWAY 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	69/186 (37%)
		Cys-loop	185..199	CDD:349809	11/13 (85%)
		Neur_chan_memb	274..588	CDD:460753	78/346 (23%)
CG8916	NP_573090.3	LIC	92..598	CDD:455710	170/589 (29%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	70/187 (37%)
		Cys-loop	233..247	CDD:349808	11/13 (85%)